Epigenetic and Metabolomic Changes in Childhood Cancer Survivors

2019-03-13 04:04:23 | BioPortfolio


The purpose of this research study is to try and identify markers in childhood cancer survivors to help predict if they will develop late effects from their cancer treatment.


This is a pilot study to obtain preliminary data that will be used to apply for a larger grant to fund the full study with an adequate sample size for analysis.

Specific Aim 1. What are the epigenetic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage.

Specific Aim 2. Compare the metabolomic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage.

Study Design


Childhood Cancer


One-time blood draw, Evaluation of CpG methylation, Metabolomic analysis


Comprehensive Cancer Center of Wake Forest University
North Carolina
United States




Wake Forest University Health Sciences

Results (where available)

View Results


Published on BioPortfolio: 2019-03-13T04:04:23-0400

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