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Epigenetic and Metabolomic Changes in Childhood Cancer Survivors

2019-03-13 04:04:23 | BioPortfolio

Summary

The purpose of this research study is to try and identify markers in childhood cancer survivors to help predict if they will develop late effects from their cancer treatment.

Description

This is a pilot study to obtain preliminary data that will be used to apply for a larger grant to fund the full study with an adequate sample size for analysis.

Specific Aim 1. What are the epigenetic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage.

Specific Aim 2. Compare the metabolomic differences between children treated for childhood cancers and healthy controls matched for age, sex, ethnicity, geographic region, and tanner stage.

Study Design

Conditions

Childhood Cancer

Intervention

One-time blood draw, Evaluation of CpG methylation, Metabolomic analysis

Location

Comprehensive Cancer Center of Wake Forest University
Winston-Salem
North Carolina
United States
27157

Status

Recruiting

Source

Wake Forest University Health Sciences

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-03-13T04:04:23-0400

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