Biodiversity Intervention and Atopic Sensitization

2019-03-18 05:18:25 | BioPortfolio


Children will receive biodiversity intervention or placebo. The proof of concept trial is double blind. Intervention will start at the age of 2 months and last 10 months. Children will be randomized to arms. IgE sensitization is the primary outcome.


Newborns will start to be exposed to biodiversity intervention or placebo at the age of two months. The proof of concept trial will be double blind. Intervention will start at the age of 2 months and it will end when children become 12 months old. Children will be randomized to the two arms. IgE sensitization is the primary outcome at the age of two and three years.

Study Design




Nature-based materials


Not yet recruiting


Helsinki University

Results (where available)

View Results


Published on BioPortfolio: 2019-03-18T05:18:25-0400

Clinical Trials [314 Associated Clinical Trials listed on BioPortfolio]

Use Cord Blood Single Nucleotide Polymorphism to Predict the Later Development of Atopy and Allergy

The aim of our study was firstly to detect in cord bloods the polymorphism of genes related to atopy and allergic diseases and to examine their mutual interaction and their associations wi...

Nature-based Solutions for Work-related Stress

Although exposure to nature has restorative effects on human health, beneficial effects of nature-based interventions in the working environment have been underexplored. The investigators ...

Markers of Atopy in Children With Presumed Early Exposure to Allergens, Unhygienic Conditions, and Infections

There are many studies regarding possible causes of increasing trend in frequency of allergic diseases in the last three decades. Main causes of this trend are: decrease of infectious dise...

Atopy Patch Test in Normal Population : Pilot Study

Atopy patch test in normal population

RCT to Evaluate Biocompatibility of Resin-based Dental Materials

In this randomized clinical trial, we will compare the biocompatibilty of 2 materials used for dental restorations: glass-ionomer vs resin-based composites. Urine and saliva samples will ...

PubMed Articles [20806 Associated PubMed Articles listed on BioPortfolio]

Efficacy of Prednisolone in bronchiolitis with and without family history of atopy.

To determine decrease in respiratory distress and hospital stay in bronchiolitis patients with and without family history of atopy when treated with prednisolone.

Opportunities and Challenges in DNA-Hybrid Nanomaterials.

Nature has inspired the development of many life-like materials. Although still simplistic, key biological functionalities have been incorporated, enabling a wide variety of applications. DNA-based sy...

Hydrogel-based commercial products for biomedical applications: a review.

Hydrogels are hydrophilic polymer networks, able to absorb large amount of water, increasing their volume and showing a plethora of different material behaviors. Since their first practical applicatio...

Performance enhancement of HS-based autotrophic denitrification with bio-gaseous CO as sole carbon source through new pH adjustment materials.

HS-based denitrification could achieve synchronous removal of nitrate and HS and had been regarded as an efficient way for biogas desulfurization and wastewater denitrification. Using CO in biogas as ...

Evidence linking atopy and staphylococcal superantigens to the pathogenesis of lymphomatoid papulosis, a recurrent CD30+ cutaneous lymphoproliferative disorder.

Primary cutaneous CD30+ lymphoproliferative disorders (CD30CLPD) are the second most common type of cutaneous T cell lymphoma (CTCL) and include lymphomatoid papulosis (LyP) and primary cutaneous anap...

Medical and Biotech [MESH] Definitions

Organic polymeric materials which can be broken down by naturally occurring processes. This includes plastics created from bio-based or petrochemical-based materials.

Materials fabricated by BIOMIMETICS techniques, i.e., based on natural processes found in biological systems.

The procedure established to evaluate the health status and risk factors of the potential DONORS of biological materials. Donors are selected based on the principles that their health will not be compromised in the process, and the donated materials, such as TISSUES or organs, are safe for reuse in the recipients.

The transport of materials through a cell. It includes the uptake of materials by the cell (ENDOCYTOSIS), the movement of those materials through the cell, and the subsequent secretion of those materials (EXOCYTOSIS).

An interdisciplinary study of the microstructure and composition of various materials such as metals, semiconductors, ceramics, and polymers, in relation to their macromolecular physical and chemical properties. Materials science enables the custom creation of new materials with specific properties and uses.

More From BioPortfolio on "Biodiversity Intervention and Atopic Sensitization"

Quick Search

Relevant Topic

Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Searches Linking to this Trial