A Study to Assess Efficay and Safety of LC350189 Different Doses in Gout Patients With Hyperuricemia

2019-05-06 17:20:30 | BioPortfolio


The aim of this 12-week randomized multicenter double-blind double-dummy parallel group placebo and active comparator-controlled dose finding study is to assess the efficacy and safety of four different doses of LC350189 in subjects with hyperuricemia and a diagnosis of gout.

Study Design




Xanthine Oxidase Inhibitor, Xanthine Oxidase Inhibitor, Placebo


Not yet recruiting


LG Chem

Results (where available)

View Results


Published on BioPortfolio: 2019-05-06T17:20:30-0400

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Medical and Biotech [MESH] Definitions

A thiazole derivative and inhibitor of XANTHINE OXIDASE that is used for the treatment of HYPERURICEMIA in patients with chronic GOUT.

A xanthine oxidase inhibitor.

An oxidation product, via XANTHINE OXIDASE, of oxypurines such as XANTHINE and HYPOXANTHINE. It is the final oxidation product of purine catabolism in humans and primates, whereas in most other mammals URATE OXIDASE further oxidizes it to ALLANTOIN.

A XANTHINE OXIDASE inhibitor that decreases URIC ACID production. It also acts as an antimetabolite on some simpler organisms.

A metallic element with the atomic symbol Mo, atomic number 42, and atomic weight 95.94. It is an essential trace element, being a component of the enzymes xanthine oxidase, aldehyde oxidase, and nitrate reductase. (From Dorland, 27th ed)

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