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A Phase 3, Randomized, Double Blinded, Active Controlled, Multicenter Study to Evaluate the Efficacy, Safety & Pharmacokinetics of EXPAREL vs Bupivacaine Administered as Combined Sciatic and Femoral Triangle Nerve Block, For Postsurgical Analgesia in Subj

2019-05-22 19:56:22 | BioPortfolio

Published on BioPortfolio: 2019-05-22T19:56:22-0400

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Pericapsular Exparel for Pain Relief in Bunionectomy and Related Procedures

Exparel is an FDA-approved local anesthetic (bupivacaine), in a long-release formulation. In this study the investigators plan to determine the ability of Exparel to control post-operative...

Postoperative Pain Control After Enucleation or Evisceration

There is a new form of bupivacaine, called Exparel, which can be injected into the eye socket during surgery and may provide pain relief for up to 72 hours. The purpose of the study is to ...

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EXPAREL Post-tonsillectomy Clinical Trial

Tonsillectomy is one of the most commonly performed surgical procedures in the United States. The primary indications for tonsillectomy in the adult population include recurrent pharyngiti...

Intraoperative Liposomal Bupivacaine vs. Bupivacaine for Total Hip Replacement Pain Management

The purpose of this study is to compare two medications currently injected intra-operatively to help decrease pain after surgery in patients undergoing a primary total hip replacement (THR...

PubMed Articles [2737 Associated PubMed Articles listed on BioPortfolio]

Neurotoxicity of intraneural injection of bupivacaine liposome injectable suspension versus bupivacaine hydrochloride in a porcine model.

To test whether neurotoxic effects of a bupivacaine liposome injectable suspension differ from those of a standard formulation of bupivacaine hydrochloride (HCl) after intraneural injection into the s...

Liposomal Bupivacaine vs. Bupivacaine Hydrochloride with Lidocaine During Midurethral Sling Placement: a Randomized Controlled Trial.

The primary objective was to study the effects of liposomal bupivacaine (LB) compared to bupivacaine HCL with lidocaine on postoperative day 1 pain scores.

Effect of Long-Term Intrathecal Bupivacaine Infusion on Blood Pressure.

The local anesthetic bupivacaine is a common analgesic adjuvant medication used in combination with opioids in intrathecal drug delivery systems (IDDSs). While the acute effects of spinal bupivacaine ...

Cost-Utility Study of the Economics of Bunion Correction Surgery.

Bunion correction surgery is a very common procedure to improve patients' pain and physical function attributable to a misaligned first metatarsophalangeal joint. The objective of this study was to ap...

Liposomal Bupivacaine Utilization in Total Knee Replacement Does Not Decrease Length of Hospital Stay.

Liposomal bupivacaine has reportedly been used as an adjunct for perioperative pain management in total knee replacement (TKR). The purpose of our single-blind, prospective study is to show that wound...

Medical and Biotech [MESH] Definitions

Intradermal injection of a heated (pasteurized) saline suspension of sarcoid tissue obtained from a sarcoid spleen or lymph node. In patients with active sarcoidosis a dusky red nodule develops slowly over the next few weeks at the injection site. Histologic examination, an essential part of the complete test, reveals sarcoid tissue.

A pharmaceutical preparation of sitagliptin phosphate and metformin hydrochloride that is used in the treatment of TYPE 2 DIABETES.

Adverse reactions that occur initially at the site of injection or infusion. Milder type is confined to a local allergic flare reaction. A more severe reaction is caused by extravasation of VESICANTS from the blood vessel at the site of injection and can cause damage to the surrounding tissue. In tumor flare reaction symptoms involve well beyond the injection site such as an increase in the tumor size and tumor markers levels, bone pain, and HYPERCALCEMIA.

Abnormal swelling of the inner aspect of the first metatarsal head affecting the first METATARSOPHALANGEAL JOINT.

A widely used local anesthetic agent.

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