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Drug-Drug Interaction Study of Rucaparib, Rosuvastatin and Oral Contraceptives

2019-05-21 20:22:17 | BioPortfolio

Published on BioPortfolio: 2019-05-21T20:22:17-0400

Clinical Trials [758 Associated Clinical Trials listed on BioPortfolio]

Absorption, Metabolism, and Excretion Following a Single Oral Dose of [14C]-Rucaparib

The purpose of this study is to characterize the mass balance, absorption, metabolism, and elimination pathways of orally administered [14C] rucaparib followed by cycle by cycle treatment ...

Pharmacokinetic Drug-Drug Interaction Study of Rucaparib

The purpose of this study is to assess pharmacokinetic concentrations of multiple probes alone followed by assessment of the same drug pharmacokinetic concentrations when the patient has s...

Ovarian Function and Reserve Parameters After Discontinuation of Long-term Use of Oral Contraception

The aim of this study is to investigate whether there is a correlation between anti-Müllerian hormone during long-term use of combined oral contraceptives and the recovery time before rec...

Effects of Drospirenone-containing or -Not Containing Combined Oral Contraceptives on General and Sexual Well-being

The purpose of this study is to evaluate the symptoms and satisfaction for women taking drospirenone (DRSP)-containing combined oral contraceptives in comparison with women taking other ki...

Long-Term Active Surveillance Study for Oral Contraceptives (LASS)

The objective of this study is to characterize and compare the risks of long-term use of oral contraceptives containing drospirenone and of other established oral contraceptives.

PubMed Articles [4674 Associated PubMed Articles listed on BioPortfolio]

No evidence that women using oral contraceptives have weaker preferences for masculine characteristics in men's faces.

Previous research has suggested that women using oral contraceptives show weaker preferences for masculine men than do women not using oral contraceptives. Such research would be consistent with the h...

Altered pharmacokinetics of combined Oral contraceptives in obesity - multi-study assessment.

To evaluate the pharmacokinetics (PK) of levonorgestrel-containing combined oral contraceptives (COCs) in obese women.

Evaluation of Drug-Drug Interactions of Rucaparib and CYP1A2, CYP2C9, CYP2C19, CYP3A, and P-gp Substrates in Patients With an Advanced Solid Tumor.

This phase 1 study (CO-338-044; NCT02740712), conducted in patients with an advanced solid tumor, evaluated the effect of the poly(ADP-ribose) polymerase inhibitor rucaparib on the pharmacokinetics of...

Sexual function and combined oral contraceptives - a randomised, placebo-controlled trial.

The effect of combined oral contraceptives (COC) on female sexuality has long been a matter of discussion, but placebo-controlled studies are lacking. Thus, the aim of the present study was to investi...

Strategies to improve adherence and continuation of shorter-term hormonal methods of contraception.

Worldwide, hormonal contraceptives are among the most popular reversible contraceptives. Despite high perfect-use effectiveness rates, typical-use effectiveness rates for shorter-term methods such as...

Medical and Biotech [MESH] Definitions

Oral contraceptives which owe their effectiveness to hormonal preparations.

Oral contraceptives which owe their effectiveness to synthetic preparations.

Drugs administered orally and sequentially for contraceptive purposes.

Fixed drug combinations administered orally for contraceptive purposes.

The 3-methyl ether of ETHINYL ESTRADIOL. It must be demethylated to be biologically active. It is used as the estrogen component of many combination ORAL CONTRACEPTIVES.

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