Early Signs of Altitude Illness in Patients With COPD

2019-05-27 22:13:11 | BioPortfolio


This study evaluates whether structured self-monitoring (SSM) by a symptom checklist in combination with a pulse oximeter worn at the wrist allows lowlanders with COPD to accurately identify whether or not they will experience an altitude-related illness during altitude travel.


This study evaluates whether structured self-monitoring (SSM) by a symptom checklist in combination with a pulse oximeter worn at the wrist allows lowlanders with COPD to accurately identify whether or not they will experience an altitude-related illness during altitude travel. After baseline evaluation at 760 m, patients will travel by bus within 3-5 h to the Tuja Ashu high altitude clinic at 3'100 m and stay there for 2 days. During this period, participants will perform SSM. They are instructed to report to study personnel if they fulfill predefined criteria for impeding altitude-related illness.

A planned interim analysis will be performed after the first year of the study or after completion of study by 80 participants, whichever comes first to allow any necessary adaptations of the sample size or terminate the study early for futility or high accuracy of the index test.

Study Design


Chronic Obstructive Pulmonary Disease


Structured self-monitoring during an altitude ascent and stay at high altitude


National Center of Cardiology and Internal Medicine




University of Zurich

Results (where available)

View Results


Published on BioPortfolio: 2019-05-27T22:13:11-0400

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