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Time-course of Mitochondrial Biogenic Gene and Protein Expression in Exercised Human Skeletal Muscle

2019-06-11 01:14:33 | BioPortfolio

Summary

This study examines the impact of exercise intensity on the 12-hour time-course of mitochondrial biogenic gene and protein expression in human skeletal muscle. Briefly, participants will perform two experimental sessions involving an acute bout of work-matched low- or high-intensity interval cycling exercise in a randomized crossover fashion, two weeks apart. Skeletal muscle biopsies will be obtained from the vastus lateralis (3 from each leg) before and 1, 3, 6, 9, and 12 hours post-exercise. Changes in the expression of various transcription factors and mitochondrial proteins will be examined at the mRNA and protein level to determine the time-course of changes in these factors differs between exercise protocols of different intensities.

Study Design

Conditions

Mitochondrial Biogenesis

Intervention

LO, HI

Location

School of Kinesiology and Health Studies
Kingston
Ontario
Canada
K7L3N6

Status

Recruiting

Source

Queen's University

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-06-11T01:14:33-0400

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