Advertisement

Topics

Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection

2019-06-18 02:44:26 | BioPortfolio

Published on BioPortfolio: 2019-06-18T02:44:26-0400

Clinical Trials [2592 Associated Clinical Trials listed on BioPortfolio]

Prevention of Kidney Transplant Rejection

The purpose of this study is to see how effective 2 drugs, irbesartan and pravastatin, are at slowing kidney transplant failure. Many kidney transplant patients have some type of chronic ...

Belatacept to Prevent Organ Rejection in Kidney Transplant Patients

Belatacept is an experimental medication shown in clinical trials to have immune system suppression properties in people who have had kidney transplants. This study will determine whether ...

Genomics of Chronic Renal Allograft Rejection (The GoCAR Study)

Doctors have had success preventing certain types of kidney transplant rejection by suppressing the immune system. However, an individual's genetic make-up and the strength of an immune r...

Combined Kidney and Bone Marrow Transplantation to Prevent Kidney Transplant Rejection

In small initial studies, combined kidney and bone marrow transplants from the same donor have permitted some individuals to stop taking anti-rejection medicines without rejecting their tr...

Metabolite Biomarkers Related to Acute Rejection in Kidney Transplantation

The development of acute rejection can only be considered in cases with increasing serum creatinine in patients with kidney transplantation. However, the serum creatinine itself is not spe...

PubMed Articles [3917 Associated PubMed Articles listed on BioPortfolio]

Repeat kidney transplant recipients with active rejection have elevated donor-derived cell-free DNA.

In 2015, 13% of recipients of kidney transplants in the United States were repeat transplants for prior allograft failure (1). These repeat kidney transplant recipients (RKTR) have inferior graft surv...

Donor Derived HLA-G Polymorphisms Have a Significant Impact on Acute Rejection in Kidney Transplantation.

Human leucocyte antigen G (HLA-G) is a non-classical HLA-class I antigen that exerts immunoregulatory functions. The polymorphisms 14-base pair (bp) insertion/deletion (ins/del) (rs1704) and +3142C>G ...

Incidence and risk factors associated with cytomegalovirus infection after thetreatment of acute rejection during the first year in kidney transplant recipients receiving preemptive therapy.

The complex interaction betweencytomegalovirus (CMV) infection and acute rejection after kidney transplantation is well recognized.

Non-HLA agonistic anti-angiotensin II type 1 receptor antibodies induce a distinctive phenotype of antibody-mediated rejection in kidney transplant recipients.

Anti-angiotensin II type 1 receptor (AT1R) antibodies have been associated with allograft rejection. We hypothesized that circulating AT1R antibodies might identify kidney transplant recipients at inc...

Acute cellular rejection treatment outcomes stratified by Banff grade in pediatric kidney transplant.

There are limited data to guide optimal treatment strategies for acute cellular rejection (ACR) based on Banff grade for pediatric kidney transplant recipients. This report reviews a large pediatric t...

Medical and Biotech [MESH] Definitions

A derivative of sirolimus and an inhibitor of TOR SERINE-THREONINE KINASES. It is used to prevent GRAFT REJECTION in heart and kidney transplant patients by blocking cell proliferation signals. It is also an ANTINEOPLASTIC AGENT.

An immune response with both cellular and humoral components, directed against an allogeneic transplant, whose tissue antigens are not compatible with those of the recipient.

Identification of the major histocompatibility antigens of transplant DONORS and potential recipients, usually by serological tests. Donor and recipient pairs should be of identical ABO blood group, and in addition should be matched as closely as possible for HISTOCOMPATIBILITY ANTIGENS in order to minimize the likelihood of allograft rejection. (King, Dictionary of Genetics, 4th ed)

A group of antigens that includes both the major and minor histocompatibility antigens. The former are genetically determined by the major histocompatibility complex. They determine tissue type for transplantation and cause allograft rejections. The latter are systems of allelic alloantigens that can cause weak transplant rejection.

Non-acceptance, negative attitudes, hostility or excessive criticism of the individual which may precipitate feelings of rejection.

More From BioPortfolio on "Study for the Prediction of Active Rejection in Organs Using Donor-derived Cell-free DNA Detection"

Advertisement
Quick Search
Advertisement
Advertisement

 

Searches Linking to this Trial