Efficacy and Safety of Plasma Exchange Compared to Standard Medical Therapy in Patients With Severe Drug Induced Liver Injury With or Without Underlying Chronic Liver Disease.

2019-07-16 10:38:49 | BioPortfolio


In this randomized study subject will be randomized into two groups Group A will receive Standard Medical Treatment (Albumin + High Caloric Diet) Group B will continue Standard Medical Treatment with High Volume Plasma Exchange. All other interventions will be at the discretion of clinicians.

Study Design


Chronic Liver Disease


High Volume Plasma Exchange, Standard Medical Treatment


Institute of Liver & Biliary Sciences
New Delhi




Institute of Liver and Biliary Sciences, India

Results (where available)

View Results


Published on BioPortfolio: 2019-07-16T10:38:49-0400

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Medical and Biotech [MESH] Definitions

Removal of plasma and replacement with various fluids, e.g., fresh frozen plasma, plasma protein fractions (PPF), albumin preparations, dextran solutions, saline. Used in treatment of autoimmune diseases, immune complex diseases, diseases of excess plasma factors, and other conditions.

Volume of PLASMA in the circulation. It is usually measured by INDICATOR DILUTION TECHNIQUES.

Volume of circulating BLOOD. It is the sum of the PLASMA VOLUME and ERYTHROCYTE VOLUME.

A plasma membrane exchange glycoprotein transporter that functions in intracellular pH regulation, cell volume regulation, and cellular response to many different hormones and mitogens.

High molecular weight, insoluble polymers which contain functional groups that are capable of undergoing exchange reactions (ION EXCHANGE) with either cations or anions.

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