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Evaluation of Amphotericin B in Optisol-GS for Prevention of Post-Keratoplasty Fungal Infections.

2019-07-18 10:31:12 | BioPortfolio

Summary

With the increasing popularity of endothelial keratoplasty, a coincident increase in the rate of fungal infections post-keratoplasty has been seen in the United States. In this study, the eye bank will harvest pairs of donor corneas and randomize one cornea from each pair to be stored in Optisol-GS per Eye Bank Association of America guidelines. The eye bank will add amphotericin B 0.255 μg/mL (antifungal) to the storage solution for the mate cornea. The study donor corneas will be assigned to participants who are scheduled to undergo Descemet membrane endothelial keratoplasty. The surgeons, participants, and evaluators will remain masked regarding the donor cornea storage solution assignment. The participants will be followed for 6 months.

Study Design

Conditions

Fuchs' Endothelial Dystrophy

Intervention

Amphotericin B

Location

Price Vision Group
Indianapolis
Indiana
United States
46260

Status

Withdrawn

Source

Cornea Research Foundation of America

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-07-18T10:31:12-0400

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