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Ebola Vaccine Trial (Ad26.ZEBOV/MVA-BN-Filo)

2019-07-25 11:52:33 | BioPortfolio

Summary

An open-label, single arm phase II study of the candidate Ebola Vaccine Ad26.ZEBOV/MVA-BN®-Filo

Description

This is an interventional, single arm, open-label, non-randomized, phase II study to accumulate additional data on immunogenicity and safety of Ad26.ZEBOV/MVA-BN®-Filo against Ebola virus disease.

It also has a qualitative component to better understand knowledge about Ebola virus disease and the perception and attitudes towards the vaccine amongst participants (Healthcare and Frontline workers).

Study Design

Conditions

Ebola Virus Disease

Intervention

Ad26.ZEBOV/MVA-BN-Filo

Location

MRC/UVRI & LSHTM Uganda Research Unit
Entebbe
Uganda

Status

Not yet recruiting

Source

MRC/UVRI Uganda Research Unit on Aids

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-07-25T11:52:33-0400

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Medical and Biotech [MESH] Definitions

An Ig domain-containing membrane receptor for HEPATITIS A VIRUS; EBOLA VIRUS; MARBURG VIRUS; and DENGUE VIRUS. It may also function to modulate ASTHMA and HYPERSENSITIVITY.

A highly fatal, acute hemorrhagic fever, clinically very similar to MARBURG VIRUS DISEASE, caused by EBOLAVIRUS, first occurring in the Sudan and adjacent northwestern (what was then) Zaire.

Vaccines or candidate vaccines used to prevent EBOLA HEMORRHAGIC FEVER.

A genus of FLAVIVIRIDAE, also known as mucosal disease virus group, which is not arthropod-borne. Transmission is by direct and indirect contact, and by transplacental and congenital transmission. Species include BORDER DISEASE VIRUS, bovine viral diarrhea virus (DIARRHEA VIRUS, BOVINE VIRAL), and CLASSICAL SWINE FEVER VIRUS.

A genus in the family FILOVIRIDAE consisting of several distinct species of Ebolavirus, each containing separate strains. These viruses cause outbreaks of a contagious, hemorrhagic disease (HEMORRHAGIC FEVER, EBOLA) in humans, usually with high mortality.

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