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A Study of Single and Multiple Ascending Doses of KBL697 in Healthy Subjects

2019-08-19 19:46:43 | BioPortfolio

Summary

The study is designed to investigate the safety and tolerability of KBL697 in healthy volunteers. KBL697 has been developed as a potential new treatment for atopic dermatitis (AD).

Description

This is a randomized double-blind, placebo-controlled, single centre Phase I study.

Thirty-six (36) subjects are planned to be randomised at

1 site across the 2 parts of the study as follows:

- Part A (Single Ascending Dose (SAD) in healthy subjects)

- Part B (Multiple Ascending Doses (MAD) in healthy subjects)

Study Design

Conditions

Atopic Dermatitis (AD)

Intervention

KBL697, KBL697, KBL697, KBL697

Location

Nucleus Network
Melbourne
Victoria
Australia
3004

Status

Not yet recruiting

Source

KoBioLabs

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-08-19T19:46:43-0400

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Medical and Biotech [MESH] Definitions

A disseminated vesicular-pustular eruption caused by the herpes simplex virus (HERPESVIRUS HOMINIS), the VACCINIA VIRUS, or Varicella zoster (HERPESVIRUS 3, HUMAN). It is usually superimposed on a preexisting, inactive or active, atopic dermatitis (DERMATITIS, ATOPIC).

The widespread involvement of the skin by a scaly, erythematous dermatitis occurring either as a secondary or reactive process to an underlying cutaneous disorder (e.g., atopic dermatitis, psoriasis, etc.), or as a primary or idiopathic disease. It is often associated with the loss of hair and nails, hyperkeratosis of the palms and soles, and pruritus. (From Dorland, 27th ed)

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