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AlloSure for the Monitoring of Antibody Mediated Processes After Kidney Transplantation

2019-08-17 19:30:39 | BioPortfolio

Summary

This is a prospective cohort observational study to assess the role of AlloSure Donor Derived Cell Free DNA (ddcfDNA) assay in the monitoring of three high-risk groups of patients for antibody mediated processes. The AlloSure assay will be combined with the AlloMAP assay (PAXgene blood sample); which is the first in history FDA-cleared genomic solid organ transplantation rejection blood test (AlloMap). Additionally, inflammatory cytokines will be determined. The combination of the three assays will provide a comprehensive molecular diagnostic and prognostic approach to antibody-mediated processes after renal transplantation.

AlloMap Kidney is a lab-developed test and will be provided by CareDx, Inc. located at Brisbane, CA, and is designed, manufactured and used within a single CareDx laboratory. AlloMap Kidney is currently provided as "For Research use only" test and results are not intended for clinical diagnosis or patient management for "KidneyCare", which is the AlloSure-Kidney and AlloMap-Kidney tests combined.

Study Design

Conditions

Kidney Transplant Failure and Rejection

Intervention

AlloSure ddcfDNA assay, AlloMap assay, Inflammatory Cytokines

Location

University of Wisconsin - Madison
Madison
Wisconsin
United States
53705

Status

Not yet recruiting

Source

University of Wisconsin, Madison

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-08-17T19:30:39-0400

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