Topics

Topical Ruxolitinib Evaluation in Vitiligo Study 2 (TRuE-V2)

2019-08-18 20:09:24 | BioPortfolio

Summary

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adolescent and adult participants with non-segmental vitiligo for whom total body involved vitiligo area (facial and nonfacial) does not exceed 10% body surface area (BSA).

Study Design

Conditions

Non-segmental Vitiligo

Intervention

Ruxolitinib cream, Vehicle

Status

Not yet recruiting

Source

Incyte Corporation

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-08-18T20:09:24-0400

Clinical Trials [974 Associated Clinical Trials listed on BioPortfolio]

Topical Ruxolitinib Evaluation in Vitiligo Study 1 (TRuE-V1)

The purpose of this study is to evaluate the efficacy and safety of ruxolitinib cream in adolescent and adult participants with non-segmental vitiligo for whom total body involved vitiligo...

Topical Ruxolitinib for the Treatment of Vitiligo

The purpose of this study is to determine if topical ruxolitinib 1.5% will provide repigmentation in vitiligo lesions.

TRuE AD2 - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis

The purpose of this study is to assess the efficacy and safety of ruxolitinib cream in adolescents and adults with atopic dermatitis (AD).

TRuE AD1 - An Efficacy and Safety Study of Ruxolitinib Cream in Adolescents and Adults With Atopic Dermatitis

The purpose of this study is to assess the efficacy and safety of ruxolitinib cream in adolescents and adults with atopic dermatitis (AD).

Bimatoprost 0.03% Solution With NB-UVB Versus Their Use With Fractional Carbon Dioxide Laser in Treatment of Generalized Vitiligo

Vitiligo is a chronic disorder of pigmentation characterized by the development of white macules on the skin due to loss of epidermal melanocytes. It affects approximately 0.5%-2% of gener...

PubMed Articles [1289 Associated PubMed Articles listed on BioPortfolio]

Palmoplantar vitiligo: an overlooked entity.

Vitiligo, a disease characterized by a progressive loss of melanocytes can be classified into three major forms, non-segmental (NSV), segmental, and mixed. NSV can be divided in subtypes, including ge...

Excimer stamp test distinguishing between nevus depigmentosus and segmental vitiligo.

It is often challenging to distinguish between nevus depigmentosus (ND) and segmental vitiligo (SV), because both are unilateral and are primarily observed in children. Although a skin biopsy provides...

IL-17A is not a treatment target in progressive vitiligo.

Multiple reports confirm elevated circulating IL-17 levels and increased numbers of Th17 lymphocytes in patients with non-segmental vitiligo. Additionally, melanocyte damaging characteristics have bee...

A pilot study of 2% tofacitinib cream with narrow-band UVB for the treatment of facial vitiligo.

Stable segmental vitiligo treated with punch mini-grafts and narrow band UVB phototherapy.

Medical and Biotech [MESH] Definitions

A frozen dairy food made from cream or butterfat, milk, sugar, and flavorings. Frozen custard and French-type ice creams also contain eggs.

A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Pigmenting photosensitizing agent obtained from several plants, mainly Psoralea corylifolia. It is administered either topically or orally in conjunction with ultraviolet light in the treatment of vitiligo.

A synthetic, non-steroidal estrogen structurally related to stilbestrol. It is used, usually as the cream, in the treatment of menopausal and postmenopausal symptoms.

A vasodilator that also has bronchodilatory action. It has been employed in the treatment of angina pectoris, in the treatment of asthma, and in conjunction with ultraviolet light A, has been tried in the treatment of vitiligo. (From Martindale, The Extra Pharmacopoeia, 30th ed, p1024)

More From BioPortfolio on "Topical Ruxolitinib Evaluation in Vitiligo Study 2 (TRuE-V2)"

Quick Search

Searches Linking to this Trial