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To demonstrate the effect of non invasive vagus nerve (VNS) stimulation on heart rate variability and MSNA signal.
First part: Assessment of the muscle sympathetic nerve activity (MSNA) at baseline using microneurography performed on the superficial peroneal nerve.
Second part: Acquisition of the MSNA signal during non-invasive VNS and apnea. Non-invasive VNS is performed using several frequencies of stimulation. Maximal and voluntaries apnea are performed at the end of the expiration.
Continuous recording of the following parameters:
- non-invasive arterial blood pressure
- R-R interval
- MSNA activity
- respiratory curve signal
- respiratory rate, oxygen saturation
Autonomic Nervous System
Modulation of muscle sympathetic nerve activity
Erasme University Hospital
Université Catholique de Louvain
Published on BioPortfolio: 2019-08-20T20:17:12-0400
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