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Phase 2a Respiratory Syncytial Virus (RSV) Human Challenge Study of MK-1654 in Healthy Participants (MK-1654-005)

2019-09-17 02:47:37 | BioPortfolio

Summary

The primary objective of this study is to determine if a single intravenous (IV) dose of MK-1654 when administered at 1 of 4 dose levels results in a reduction in viral load after intranasal inoculation (with RSV A Memphis 37b) compared to IV placebo. It is hypothesized that at least 1 of the 4 dose levels of MK-1654 given prior to inoculation will reduce the area under the viral load-time curve (VL-AUC) from Day 2 through Day 11 (inclusive) compared to placebo.

Study Design

Conditions

Respiratory Syncytial Viruses

Intervention

MK-1654, Placebo, RSV-A Memphis 37b

Status

Not yet recruiting

Source

Merck Sharp & Dohme Corp.

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-09-17T02:47:37-0400

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