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Allocation: Randomized Endpoint classification: Efficacy study Masking: Open label Primary purpose: Treatment Primary endpoint: Incidence of reaching the target serum trough concentration Secondary endpoint: Clinical efficiency, Antibiotic use, acute kidney injury.
This is a prospective randomized control trial. There are two groups, study group and control group. Patients of study group accepted vancomycin strategies decided by a serum trough concentration model, and patients of control group accepted vancomycin dosage decided by attending physician. The primary endpoint is the incidence of reaching the target serum trough concentration, the secondary endpoint are clinical efficiency, antibiotic use and side effects such as acute kidney injury, etc.
Not yet recruiting
Peking University Third Hospital
Published on BioPortfolio: 2019-09-15T03:11:17-0400
To determine if linezolid is superior to vancomycin in the treatment of nosocomial (acquired in the hospital) pneumonia due to MRSA in adult subjects. Subjects entered in to the study will...
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The dose amount of poisonous or toxic substance or dose of ionizing radiation required to kill 50% of the tested population.
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Poisoning by staphylococcal toxins present in contaminated food.
A treatment schedule in which the total dose of radiation is divided into large doses.
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