Epigenetic Changes in Psychotherapy of Adolescents With Borderline Personality Pathology

2019-09-25 06:13:40 | BioPortfolio


The link between epigenetic changes as an effect of psychotherapy has been investigated recently. Genes investigated in these studies were brain-derived neurotrophic factor (BDNF), NR3C1, FKBP51, MAOA and GLUT1. Change in methylation of these genes could be a biomolecular mechanism of psychotherapy induced changes. This study project aims at providing evidence for a biological mechanism of personality disorder interventions in adolescence by investigating the link between epigenetic changes as an effect of psychotherapy. It investigates the correlation between changes in the methylation of the FKBP5 gene and psychotherapy induced changes in symptoms and functioning.

Study Design


Borderline Personality Disorder (BPD)


routine psychotherapy for Borderline Personality Disorder (BPD)


Department of Psychiatry and Mental Health, East Campus,


Not yet recruiting


University Hospital, Basel, Switzerland

Results (where available)

View Results


Published on BioPortfolio: 2019-09-25T06:13:40-0400

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