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A Phase Ⅱ Trial of Pyrotinib Combination With CDK4/6 Inhibitor SHR6390 in Patients Prior Trastuzumab-treated Advanced HER2-Positive Breast Cancer

2019-09-24 05:27:27 | BioPortfolio

Summary

The study is being conducted to evaluate the efficacy, safety and tolerability of pyrotinib combination with CDK4/6 Inhibitor SHR6390 in advanced HER2-Positive breast cancer patients who prior trastuzumab-treated.

Study Design

Conditions

Metastatic Breast Cancer

Intervention

Pyrotinib, SHR6390, Letrozole, Capecitabine

Location

Breast Cancer Center, Shandong Cancer Hospital Affiliated to Shandong University
Jinan
China
250117

Status

Recruiting

Source

Shandong Cancer Hospital and Institute

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-09-24T05:27:27-0400

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Study to Evaluate the Efficacy and Safety of CDK4/6 Inhibitor SHR6390 Combined With Pyrotinib in the Treatment of HER2-positive Advanced Breast Cancer

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Medical and Biotech [MESH] Definitions

A deoxycytidine derivative and fluorouracil PRODRUG that is used as an ANTINEOPLASTIC ANTIMETABOLITE in the treatment of COLON CANCER; BREAST CANCER and GASTRIC CANCER.

Metastatic breast cancer characterized by EDEMA and ERYTHEMA of the affected breast due to LYMPHATIC METASTASIS and eventual obstruction of LYMPHATIC VESSELS by the cancer cells.

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