Characterization of Fatty Acid Composition of Triglycerides in Patients With Hypertriglyceridemia-induced Acute Pancreatitis
Summary
) Finding a unique pattern in the triglyceride composition of patients with hypertriglyceridemia that increases the chances of getting pancreatitis and which can serve as a laboratory predictive tool for patients and define them as a at-risk population.
2) Finding the typical fatty acid composition in triglycerides for patients at high risk of pancreatic acute inflammation that can be used to develop unique drugs for pancreatic acute inflammation caused by high levels of triglycerides.
Description
The study will be conducted at the Sheba Medical Center Lipid Institute, number of participants: 10 healthy participants, 10 participants with hypertriglyceridemia without prior pancreatitis and 10 participants with hypertriglyceridemia and at least one case of severe pancreatitis in the last 5 years.
A total of 30 participants Participants who are found suitable during their visit to the Lipid Institute Clinic or during their hospitalization at Sheba Medical Center will receive an explanation of the study, will be asked to sign a consent form. And check the fatty acid levels. Healthy volunteers who meet the inclusion conditions will also be asked to sign a consent form and their blood will be taken and kept frozen for further study
Study Design
Conditions
Hypertriglyceridemia
Intervention
blood sample
Location
Lipid center
Tel HaShomer
Israel
5265601
Status
Recruiting
Source
Sheba Medical Center
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT04097990
- ClinicalTrials.gov processed this data on September 25, 2019
Published on BioPortfolio: 2019-09-26T05:42:41-0400
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Medical and Biotech [MESH] Definitions
Hypertriglyceridemia
A condition of elevated levels of TRIGLYCERIDES in the blood.
Blood Buffy Coat
The fraction of a blood sample, following CENTRIFUGATION, that is distinguished as a thin light-colored layer between the RED BLOOD CELLS, underneath it, and the PLASMA, above it. It is composed mostly of WHITE BLOOD CELLS and PLATELETS.
Erythrocyte Count
The number of RED BLOOD CELLS per unit volume in a sample of venous BLOOD.
Blood Cell Count
The number of LEUKOCYTES and ERYTHROCYTES per unit volume in a sample of venous BLOOD. A complete blood count (CBC) also includes measurement of the HEMOGLOBIN; HEMATOCRIT; and ERYTHROCYTE INDICES.
Blood Specimen Collection
The taking of a blood sample to determine its character as a whole, to identify levels of its component cells, chemicals, gases, or other constituents, to perform pathological examination, etc.
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