Improving Health Behaviors for Pediatric Cancer Survivors

2019-09-26 05:42:46 | BioPortfolio


The objective of this study is to examine the efficacy of Harvesting Hope for Kids (HH4K), a biobehavioral intervention delivered in the context of a university-based, cancer survivor garden, to increase produce intake and physical activity in survivors and caregivers.


Advances in treatment have led to a rapidly growing population of over 388,500 survivors, with 13,500 new survivors expected annually. However, chronic or long-term side effects (e.g., secondary malignancies, metabolic syndrome, cardio-pulmonary toxicities) can reduce quality of life and lead to premature death. The investigators propose that diet and fitness are two critical factors for healthy survivorship given their broad impact on late effects like obesity, fatigue, and metabolic syndrome. Despite the promise of comprehensive lifestyle interventions for children who are overweight or obese, research with survivors is limited by small samples and inconsistent effects. Novel research supports a key role for the gastrointestinal (GI) microbiome in regulating weight and health outcomes, yet no studies have examined the "obesogenic" microbiome in the context of lifestyle interventions for survivors of childhood cancer. The objective of this RCT is to examine the efficacy of Harvesting Hope for Kids (HH4K), a biobehavioral intervention delivered in the context of a university-based, cancer survivor garden, to increase produce intake and physical activity in survivors and caregivers. Families will be randomized to participate in HH4K or enhanced usual care. Dietary patterns, physical activity, cardiometabolic indices, family outcomes, and GI microbiome will be assessed and the HH4K group will demonstrate greater improved than enhanced usual care.

Study Design




Harvesting Hope for Kids (HH4K), Surviving Strong for Kids (SS4K)


Nationwide Children's Hospital
United States


Enrolling by invitation


Nationwide Children's Hospital

Results (where available)

View Results


Published on BioPortfolio: 2019-09-26T05:42:46-0400

Clinical Trials [354 Associated Clinical Trials listed on BioPortfolio]

STRONG Kids 2: A Cells-to-Society Approach to Nutrition in Early Childhood

STRONG Kids 2: A Cells to Society Approach to Nutrition Overview Using a cells-to-society approach to nutrition, this transdisciplinary project will provide unique insights into how indiv...

Little Flower Yoga for Kids: Evaluation of a Yoga and Mindfulness Program for Children With Increased Levels of Emotion Dysregulation and Inattention

An initial evaluation of Little Flower Yoga for Kids will be conducted in a small sample of 18-30 Kindergarten and First Grade students (3-5 per class) enrolled in Girls Preparatory Charte...

An Effectiveness Study of the Cool Kids Programme

The aim of the present study is to investigate the effectiveness of the Cool Kids programme after implementation in two outpatient psychiatric clinics for children in Southern Jutland, Den...

Turkish Version of Kids BESTest, Validity and Reliability for School-Aged Children

The aim of this study is to present the Turkish version of Kids-BESTest and Kids-Mini-BESTest and practice of validity and reliability on school-aged children will be performed by utilizin...

Kids SipSmartER, an Intervention to Reduce Sugar-sweetened Beverages

Overall Goal: To determine the effectiveness of Kids SIPsmartER in improving sugar-sweetened beverages behaviors among 7th grade students. Secondary aims are to determine (1) changes in se...

PubMed Articles [4899 Associated PubMed Articles listed on BioPortfolio]

Blood lactate, pH, base excess and pCO as prognostic indicators in caesarean-born kids from goats with pregnancy toxaemia.

The objective of this study was to identify the prognostic value for survival of blood parameters in the immediate post-caesarean surgery period in kids born from pregnancy toxaemia (PT) goats. This s...

Healthy Kids Cambodia - A novel approach to triage for dental care in a population with extreme caries experience.

To describe the disease experiences and treatment provided according to a set of novel triage criteria among children in the Healthy Kids Cambodia project.

Effect of selenium supplementation on attainment of puberty in Saanen male goat kids.

The aim of the study was to evaluate the effect on selenium supplementation on attainment of puberty in Saanen male goat kids. Forty Saanen male goats kids were divided into two groups: selenium suppl...

Cross-cultural adaptation and measurement properties of the Arabic version of the ABILHAND-Kids scale.

To cross-culturally adapt the ABILHAND-Kids into Arabic and to examine its measurement properties in children with cerebral palsy.

Effect of the nutritional status of Creole goats on the density-dependent prolificacy of Haemonchus contortus.

The objective of this study was to measure the effect of the nutritional status of Creole goat kids on the host responses and the nematode population established after an experimental H. contortus inf...

Medical and Biotech [MESH] Definitions

Belief in a positive outcome.

Large mammals in the family Elephantidae, with columnar limbs, bulky bodies, and elongated snouts. They are the only surviving members of the PROBOSCIDEA MAMMALS.

A family of flightless, running BIRDS, in the order Casuariiformes. The emu is the only surviving member of the family. They naturally inhabit forests, open plains, and grasslands in Australia.

Persons who have experienced a prolonged survival after serious disease or who continue to live with a usually life-threatening condition as well as family members, significant others, or individuals surviving traumatic life events.

The bestowing of tangible or intangible benefits, voluntarily and usually without expectation of anything in return. However, gift giving may be motivated by feelings of ALTRUISM or gratitude, by a sense of obligation, or by the hope of receiving something in return.

More From BioPortfolio on "Improving Health Behaviors for Pediatric Cancer Survivors"

Quick Search

Relevant Topics

  Bladder Cancer Brain Cancer Breast Cancer Cancer Cervical Cancer Colorectal Head & Neck Cancers Hodgkin Lymphoma Leukemia Lung Cancer Melanoma Myeloma Ovarian Cancer Pancreatic Cancer ...

Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Pulmonary relating to or associated with the lungs eg Asthma, chronic bronchitis, emphysema, COPD, Cystic Fibrosis, Influenza,  Lung Cancer, Pneumonia, Pulmonary Arterial Hypertension, Sleep Disorders etc Follow and track Lung Cancer News ...

Searches Linking to this Trial