Topics

Decision-making - the Benefit of Bedside CRP Within Ambulance Care

2019-09-25 06:13:27 | BioPortfolio

Summary

Patients with degreased (DGC) for ambiguous reasons receive low triage priority. Their death risk is triple. Tools are needed to identify the critically ill patients from this group. The triage used today is not effective. The bedside point-of-care measurements are CRP, lactate acid and suPAR (Soluble Urokinase Plasminogen Activator Receptor). Elevated values associate with the probability of critical illness and predict a risk of death.

Description

Purpose: To improve identification and proper prioritization of patients with non-specific symptoms prehospitally, we intend to investigate whether Q-CRP, a rapid test for CRP, correlates with time-critical states in the above-mentioned patient group alone or together with CRP, lactate and suPAR. The primary endpoint is need for hospital care.

Material: Patients over 18 years who exhibit non-specific symptoms and transported to the emergency room.

Method: In patients with unspecified conditions, defined according to the inclusion template, a venous blood sample was taken prehospitally at the scene by the EMS.

Analysis: Significance tests and regression analyzes with 95% CI were used. The diagnostic accuracy of Q-CRP, lactate, suPAR and combinations thereof were compared with optimal boundary values.

Study Design

Conditions

Critical Illness

Intervention

POC

Status

Completed

Source

Helsinki University Central Hospital

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-09-25T06:13:27-0400

Clinical Trials [713 Associated Clinical Trials listed on BioPortfolio]

Functional Outcomes in Children Post Critical Illness

Improvements in medical care have led to decreasing mortality rates in critically ill children, which have been reported to be as low as 5%. However, surviving critical illness does not ne...

Characterising Changes in Muscle Quantity and Quality in Patients Requiring ECMO Oxygen During Critical Illness

This study will identify the changes in different muscles of patients receiving Extracorporeal Membrane Oxygenation (ECMO) during critical illness and admission to Intensive Care Unit (ICU...

Skeletal Muscle Wasting and Renal Dysfunction After Critical Illness Trauma - Outcomes Study

This study aims to determine changes in kidney function during and after critical illness, comparing conventional creatinine based methods with the gold standard to accurately establish th...

Rehabilitation Following Critical Illness

The principal research question to be answered by this study is whether an exercise based rehabilitative intervention following critical illness can generate improvements in exercise capac...

Measuring Outcomes of Activity in Intensive Care

Millions of older adults are hospitalized for a critical illness each year and although they are more likely than ever to survive this illness, they commonly face significant morbidity in ...

PubMed Articles [6113 Associated PubMed Articles listed on BioPortfolio]

Exploration of muscle loss and metabolic state during prolonged critical illness: Implications for intervention?

Muscle wasting in the critically ill is up to 2% per day and delays patient recovery and rehabilitation. It is linked to inflammation, organ failure and severity of illness. The aims of this study wer...

Red blood cell distribution width provides additional prognostic value beyond severity scores in adult critical illness.

The prognostic value of red blood cell distribution width (RDW) in critical illness remains controversial. The aim of this study was to investigate the prognostic value of on-admission RDW for in-hosp...

Activation of pituitary axis according to underlying critical illness and its effect on outcome.

Critical illness is a life threatening condition inducing a severe acute physical stress. The aim of the study was to investigate the activation of pituitary axis early after ICU admission in patients...

Association of Organ Dysfunction Scores and Functional Outcomes Following Pediatric Critical Illness.

Short-term and long-term morbidity and mortality are common following pediatric critical illness. Severe organ dysfunction is associated with significant in-hospital mortality in critically ill childr...

Psychocognitive sequelae of critical illness and correlation with 3 months follow up.

Over a third of critical illness survivors manifest significant psychocognitive impairments following discharge from the intensive care unit (ICU). It is not known which patient populations are at hig...

Medical and Biotech [MESH] Definitions

A disease or state in which death is possible or imminent.

An acute or prolonged illness usually considered to be life-threatening or with the threat of serious residual disability. Treatment may be radical and is frequently costly.

Simulation of symptoms of illness or injury with intent to deceive in order to obtain a goal, e.g., a claim of physical illness to avoid jury duty.

A measure of the mortality and morbidity rates among patients who receive CRITICAL CARE and INTENSIVE CARE as determined from the date of hospital discharge or release.

Levels of severity of illness within a diagnostic group which are established by various measurement criteria.

More From BioPortfolio on "Decision-making - the Benefit of Bedside CRP Within Ambulance Care"

Quick Search

Searches Linking to this Trial