The Therapeutic Effect of Dysthyroid Optic Neuropathy

2019-09-25 06:13:32 | BioPortfolio


Thyroid associated ophthalmopathy (TAO) is a common autoimmune disorder. The pathogenesis of TAO is unclear, and studies found that T cell, B cell and monocytes, macrophages and mast cells are located in the orbital tissue of TAO. Dysthyroid optic neuropathy (DON) is the most serious complication of TAO, which can cause blurred vision, color vision and vision function damage, and affects the quality of life. Investigation of the therapeutic effect of orbital decompression may provide some clues to make the policy at treatment of DON. We explore the therapeutic effect of orbital decompression in patients with DON in both eyes.

Study Design


Thyroid Eye Disease


Orbital decompression combined with MPT


Zhongshan Opthalmic Center




Sun Yat-sen University

Results (where available)

View Results


Published on BioPortfolio: 2019-09-25T06:13:32-0400

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Medical and Biotech [MESH] Definitions

Autoantibodies that bind to the thyroid-stimulating hormone (TSH) receptor (RECEPTORS, THYROTROPIN) on thyroid epithelial cells. The autoantibodies mimic TSH causing an unregulated production of thyroid hormones characteristic of GRAVES DISEASE.

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