Early feasibility study, single-arm registry design
First-In-Human
Mitral Regurgitation
Not yet recruiting
Polares Medical SA
Published on BioPortfolio: 2019-09-26T05:42:39-0400
Prospective, observational, multi-center trial in which patients with mitral regurgitation sufficient to merit mitral valve repair will receive a surgical transvalvular, intra-annular Mitr...
Recent publications show that an adjunctive subvalvular repair during mitral annuloplasty for secondary mitral regurgitation effective in preventing recurrent regurgitation. One of these p...
The primary treatment for patients determined to have severe aortic or mitral regurgitation is surgical repair or replacement their valves. The most commonly used tool to quantify the seve...
At present, the optimal treatment strategy for heart failure patients and moderate-to-severe (3+) or severe (4+) mitral regurgitation with a class IIa recommendation for CRT is uncertain.W...
A Randomized Clinical Trial of Metoprolol in Participants With Mitral Regurgitation.
Mitral valve regurgitation (leakage of the mitral valve of the heart) is frequent and currently there is no specific medical therapy. Mitral regurgitation is a slowly progressive disease ...
Evolution of Tricuspid Regurgitation after Repair of Degenerative Mitral Regurgitation.
The fate of unrepaired tricuspid regurgitation (TR) after mitral repair (MVr) for degenerative mitral regurgitation (MR) remains highly debated. The objective of this study was to examine the progress...
Initial studies have suggested the familial clustering of mitral valve prolapse, but most of them were either community based among unselected individuals or applied non-specific diagnostic criteria. ...
Functional and Degenerative Mitral Regurgitation: One Ring Fits All?
Three-dimensional saddle-shaped annuloplasty rings have been shown to create a larger surface of leaflet coaptation in mitral valve repair (MVR) for functional mitral regurgitation (FMR) and degene...
This study sought to evaluate the effects of the Carillon device on mitral regurgitation severity and left ventricular remodeling.
Mechanisms of mitral regurgitation after percutaneous mitral valve repair with the MitraClip.
We sought to find the morphological mechanisms of recurrent mitral regurgitation (MR) after MitraClip procedure using 3D transoesophageal echocardiography (TOE).
Mitral Valve Insufficiency
Backflow of blood from the LEFT VENTRICLE into the LEFT ATRIUM due to imperfect closure of the MITRAL VALVE. This can lead to mitral valve regurgitation.
Mitral Valve Prolapse
Abnormal protrusion or billowing of one or both of the leaflets of MITRAL VALVE into the LEFT ATRIUM during SYSTOLE. This allows the backflow of blood into left atrium leading to MITRAL VALVE INSUFFICIENCY; SYSTOLIC MURMURS; or CARDIAC ARRHYTHMIA.
Mitral Valve Stenosis
Narrowing of the passage through the MITRAL VALVE due to FIBROSIS, and CALCINOSIS in the leaflets and chordal areas. This elevates the left atrial pressure which, in turn, raises pulmonary venous and capillary pressure leading to bouts of DYSPNEA and TACHYCARDIA during physical exertion. RHEUMATIC FEVER is its primary cause.
Mitral Valve Annuloplasty
A type of heart valve surgery that involves the repair, replacement, or reconstruction of the annulus of the MITRAL VALVE. It includes shortening the circumference of the annulus to improve valve closing capacity and reinforcing the annulus as a step in more complex valve repairs.
Rumination, Digestive
Regurgitation and re-chewing of previously swallowed food in RUMINANTS.
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