Pancreaze (Pancrelipase) for Patients With Pancreatic Adenocarcinoma With Cachexia and Exocrine Pancreatic Insufficiency

2019-09-26 05:42:40 | BioPortfolio


The objective of this study is to assess weight stability, functional changes, and quality of life when Pancreaze (pancrelipase) delayed-release 63,000-lipase unit capsules, for main meals, and 21,000-lipase unit capsules, for snacks, are added to standard of care in patients with exocrine pancreatic insufficiency due to pancreatic adenocarcinoma. This will be the first prospective study of this particular formulation in addition to standard of care in advanced pancreatic cancer patients. We will treat 45 consecutive patients with borderline resectable, locally advanced and advanced pancreatic cancer patients who present with weight loss and exocrine pancreatic insufficiency with this advanced formulation of Pancreaze.

Study Design


Pancreatic Adenocarcinoma




Cedars-Sinai Medical Center
Los Angeles
United States


Not yet recruiting


Cedars-Sinai Medical Center

Results (where available)

View Results


Published on BioPortfolio: 2019-09-26T05:42:40-0400

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Pancreatic enzymes (pancrelipase).

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Medical and Biotech [MESH] Definitions

A preparation of hog pancreatic enzymes standardized for lipase content.

A lesion with cytological characteristics associated with invasive adenocarcinoma but the tumor cells are confined to the GLANDULAR EPITHELIAL CELLS of origin. Adenocarcinoma in situ of the CERVIX and the LUNG are the most common.

An adenocarcinoma producing mucin in significant amounts. (From Dorland, 27th ed)

An adenocarcinoma of the thyroid gland, in which the cells are arranged in the form of follicles. (From Dorland, 27th ed)

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