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Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases

2019-09-26 05:42:41 | BioPortfolio

Summary

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure. The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.

Description

Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure.

Inclusion Criteria:

- Chronic respiratory disease (COPD, ILD, OHS...)

- Admission in ICU for acute respiratory failure

- Patient's non-opposition

Exclusion Criteria:

- Patients < 18 year-old

- Protected patients

- Pregnant women The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.

Study Design

Conditions

Acute Exacerbation of COPD

Location

Service de Pneumologie et Réanimation Médicale, Groupe Hospitalier Pitié Salpêtrière Paris, France
Paris
France
75013

Status

Not yet recruiting

Source

Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-09-26T05:42:41-0400

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