Outcomes of RV Dysfunction in Acute Exacerbation of Chronic Respiratory Diseases
Summary
Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure. The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.
Description
Observational study in patients with chronic respiratory diseases (chronic obstructive pulmonary diseases, bronchiectasis, interstitial lung diseases, neuromuscular diseases, obesity-hypoventilation syndrome...) admitted in intensive care unit for acute respiratory failure.
Inclusion Criteria:
- Chronic respiratory disease (COPD, ILD, OHS...)
- Admission in ICU for acute respiratory failure
- Patient's non-opposition
Exclusion Criteria:
- Patients < 18 year-old
- Protected patients
- Pregnant women The main objective is to determine the prevalence of right ventricular (RV) dysfunction in this population and to analyze the impact of such a complication on outcomes (survival at day-28, duration of non-invasive or mechanical ventilation, duration of hospital stay). RV function will be assessed by echocardiography at admission, after 3 days and at discharge. Plasma NT-proBNP and troponin levels will be collected.
Study Design
Conditions
Acute Exacerbation of COPD
Location
Service de Pneumologie et Réanimation Médicale, Groupe Hospitalier Pitié Salpêtrière Paris, France
Paris
France
75013
Status
Not yet recruiting
Source
Association pour le Développement et l'Organisation de la Recherche en Pneumologie et sur le Sommeil
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT04098094
- ClinicalTrials.gov processed this data on September 25, 2019
Published on BioPortfolio: 2019-09-26T05:42:41-0400
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Medical and Biotech [MESH] Definitions
Symptom Flare Up
A transient exacerbation of symptoms of an existing disease or condition.
Hyperostosis, Cortical, Congenital
A disease of young infants characterized by soft tissue swellings over the affected bones, fever, and irritability, and marked by periods of remission and exacerbation. (Dorland, 27th ed)
Pulmonary Disease, Chronic Obstructive
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Abdomen, Acute
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Pancreatitis
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