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Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Efficacy Trial of BNT411

2019-09-27 06:30:37 | BioPortfolio

Summary

This first-in-human (FIH) trial aims to establish a safe dose of BNT411 as a monotherapy and in combination with atezolizumab, carboplatin and etoposide. BNT411 is a TLR7 agonist which is expected to mount broad innate and adaptive immune reactions, especially in combination with cytotoxic therapies and immune checkpoint inhibitors.

Study Design

Conditions

Solid Tumor

Intervention

BNT411, Atezolizumab, Carboplatin, Etoposide

Status

Not yet recruiting

Source

BioNTech Small Molecules GmbH

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-09-27T06:30:37-0400

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