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The hypothesis of this clinical investigation is that in a population of men and women affected by nasolabial wrinkles, Janesse will significantly decrease the appearance of nasolabial wrinkles, after 12 weeks of treatment.
Janesse®'s action is to increase the volume of dermal-epidermal tissue based on the natural ability of hydrophilic hyaluronic acid molecules to bind to an amount of water many times greater than their weight. This allow to fill the intradermal spaces and integrate the intercellular matrix, conferring turgidity to the tissues. The cross-linking of the hyaluronic acid contained in the product has the effect of more stable and durable filling over time.
The Research Question of the present study is the following: in a population of men and women affected by nasolabial wrinkles, will cross-linked hyaluronic acid (Janesse®) significantly decrease the appearance of nasolabial wrinkles, results observed after 12 weeks?
Nasolabial Fold, Hypoplastic
Janesse® is a sterile, injectable, non-pyrogenic, re-absorbable medical product made of reticulated hyaluronic acid of non-animal origin, produced via bacterial fermentation.
Not yet recruiting
I.R.A. Istituto Ricerche Applicate S.p.A.
Published on BioPortfolio: 2019-09-30T07:06:54-0400
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