Microbiome Analysis of Constipated Versus Non-constipation Patients

2019-10-02 07:21:35 | BioPortfolio


This study intends to evaluate the microbiome of chronically constipated patients as compared to those with a non-constipated gastrointestinal system.


Biogeographically accurate microbiome sampling using the HyGIeaCare platform and an evolutionary biology informed learning platform will allow an improved discovery of bacterially derived novel molecular entities with therapeutic potential for chronic constipation. This approach intends to enhance our ability to understand the gut microbiome and use it towards developing therapeutic solutions, in comparison to traditional collection methods and taxonomic-based data analysis approaches.

Study Design


Rome IV Functional Constipation


No change in procedure except for specimen collection throughout procedure


HyGIeaCare Center
United States




HyGIeaCare, Inc.

Results (where available)

View Results


Published on BioPortfolio: 2019-10-02T07:21:35-0400

Clinical Trials [3309 Associated Clinical Trials listed on BioPortfolio]

An Evaluation of the Spectra Optia CMNC Collection Procedure

The purpose of this prospective, randomized, cross-over, multi-center study is to evaluate the performance of the Spectra Optia Apheresis System's CMNC Collection Procedure, compared to th...

Lung Transplant Specimen Repository and Data Registry Protocol

All patients enrolled in the registry will be recipients of single and double lung transplantation (bilateral sequential, heart-lung, or living related donor grafts). During the routine m...

Tissue, Blood, and Body Fluid Sample Collection From Patients With Hematologic Cancer

RATIONALE: Collecting and storing samples of tissue, blood, and body fluid from patients with cancer to study in the laboratory may help the study of cancer in the future. PURPOSE: This r...

Specimen Collection From Pregnant Women at Increased Risk for Fetal Aneuploidy

The specimen collection is designed for the purpose of the development of a noninvasive prenatal test for T21.

Comparing Specimen Collection Techniques to Screen for Sexually Transmitted Infections in Pregnant Women: A Pilot Study

The purpose of this research study is to compare two specimen collection techniques (vaginal vs. endocervical swab) to screen for sexually transmitted infections in pregnant women. Either ...

PubMed Articles [9079 Associated PubMed Articles listed on BioPortfolio]

High-quality, high-throughput cryo-electron microscopy data collection via beam tilt and astigmatism-free beam-image shift.

The throughput of cryo-electron microscopy (cryo-EM) can be improved by employing a procedure that collects beam-image shift data. However, this procedure inadvertently induces a beam tilt, thus decre...

A simplified blood culture sampling protocol for reducing contamination and costs: a randomized controlled trial.

Blood culture contamination carries risks for patients, such as unnecessary antimicrobial therapy and other additional hazards and costs. One method shown to be effective in reducing contamination is ...


The aim of the study is to identify topical issues of the regulatory framework and the application of legal provisions related to acquisition (collection) of samples for examination in criminal procee...

Minimal invasive aortic valve replacement: associations of radiological assessments with procedure complexity.

Limited aortic annulus exposure during minimal invasive aortic valve replacement (mini-AVR) proves to be challenging and contributes to procedure complexity, resulting in longer procedure times. New i...

Benefits and Pitfalls of Change From Rome III to Rome IV Criteria for Irritable Bowel Syndrome and Fecal Incontinence.

Medical and Biotech [MESH] Definitions

A set of surgical procedures performed to establish sufficient outflow to the systemic circulation in individuals with univentricular congenital heart malformations, such as HYPOPLASTIC LEFT HEART SYNDROME, and MITRAL VALVE atresia, associated with systemic outflow obstruction. Follow-on surgeries may be performed and consist of a HEMI-FONTAN PROCEDURE as the stage 2 Norwood procedure and a FONTAN PROCEDURE as the stage 3 Norwood procedure.

A condition or factor associated with a recipient that makes the use of a procedure improper or inadvisable.

Procedure in which an individual is induced into a trance-like state to relieve pain. This procedure is frequently performed with local but not general ANESTHESIA.

Changing an operative procedure from an endoscopic surgical procedure to an open approach during the INTRAOPERATIVE PERIOD.

A surgical procedure which diverts pancreatobiliary secretions via the duodenum and the jejunum into the colon, the remaining small intestine being anastomosed to the stomach after antrectomy. The procedure produces less diarrhea than does jejunoileal bypass.

More From BioPortfolio on "Microbiome Analysis of Constipated Versus Non-constipation Patients"

Quick Search

Searches Linking to this Trial