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p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT)

2019-10-01 07:55:01 | BioPortfolio

Summary

Volume and Dose De-Intensified Radiotherapy for p16+ Squamous Cell Carcinoma of the Oropharynx: A Multi-Centre, Single Arm Prospective Cohort Study

Description

De-intensified radiotherapy to a dose of 60 Gy to the primary tumour and involved lymph nodes and 54 Gy to subclinical regions at risk in 30 fractions. Omission of level IB lymph node regions from the elective nodal volumes.

Chemotherapy will be administered as per standard of care, consisting of concurrent cisplatin (high-dose: 100mg/m2 IV every 3 weeks or low-dose: 40mg/m2 IV every week) or cetuximab (at the discretion of medical oncologist).

Study Design

Conditions

Squamous Cell Carcinoma of the Oropharynx

Intervention

De-intensified chemoradiotherapy

Location

Tom Baker Cancer Centre
Calgary
Alberta
Canada

Status

Not yet recruiting

Source

AHS Cancer Control Alberta

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-01T07:55:01-0400

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