p16+ Oropharyngeal Cancer Radiation Optimization Trial Reducing Elective Treatment Volumes (PROTEcT)

2019-10-01 07:55:01 | BioPortfolio


Volume and Dose De-Intensified Radiotherapy for p16+ Squamous Cell Carcinoma of the Oropharynx: A Multi-Centre, Single Arm Prospective Cohort Study


De-intensified radiotherapy to a dose of 60 Gy to the primary tumour and involved lymph nodes and 54 Gy to subclinical regions at risk in 30 fractions. Omission of level IB lymph node regions from the elective nodal volumes.

Chemotherapy will be administered as per standard of care, consisting of concurrent cisplatin (high-dose: 100mg/m2 IV every 3 weeks or low-dose: 40mg/m2 IV every week) or cetuximab (at the discretion of medical oncologist).

Study Design


Squamous Cell Carcinoma of the Oropharynx


De-intensified chemoradiotherapy


Tom Baker Cancer Centre


Not yet recruiting


AHS Cancer Control Alberta

Results (where available)

View Results


Published on BioPortfolio: 2019-10-01T07:55:01-0400

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