School-Based Depression Prevention for Adolescents With ADHD

2019-10-01 07:55:03 | BioPortfolio


The purpose of this study is to develop a modified behavioral activation program in adolescents with ADHD to be implemented by school mental health providers in an urban, low-income school district. Subsequently we will examine its effectiveness in reducing depressive symptoms and improving emotion regulation and reward responsivity, compared to usual care.


Children with ADHD are at elevated risk for depression in adolescence and young adulthood, and this comorbidity is associated with far greater impairment than either disorder alone, including higher rates of inpatient hospitalization and increased risk for suicidal ideation and behavior. Despite these adverse outcomes, existing evidence-based interventions for ADHD have not demonstrated effects in reducing depressive symptoms nor do established depression prevention programs work as well for adolescents with ADHD. Reward responsivity (RR) and emotion regulation (ER) are two key factors demonstrated to mediate the association between ADHD and depression and are thus key targets for prevention. In an effort to address the gap between access and utilization of mental health care, which is especially stark among adolescents with ADHD, we aim to develop and test a modified behavioral activation prevention program [Behaviorally Enhancing Adolescents' Mood in Schools (BEAM-S)] that incorporates modules to directly target these purported mechanisms. In line with the Deployment-Focused Model of Intervention Development and Testing, we will develop a program that can be easily implemented and sustainable in the high school setting as delivered by school mental health staff that reduces depression and improves overall functioning in adolescents with ADHD, by way of improving RR and ER. As a first step, we will conduct focus groups with community stakeholders (e.g., school mental health providers, school administration, adolescents, parents, teachers) to develop an acceptable and sustainable selected and indicated prevention program for school staff to utilize. We will then initially train school staff to deliver this prevention program via to pilot the intervention for implementation of the prevention program in a case series to evaluate preliminary feasibility. We will then conduct a stage 1 RCT with a hybrid-type 1 implementation effectiveness design in three high schools where adolescents will be randomized to either the BEAM-S condition (n= 54) or treatment as usual (n = 54). Finally, qualitative and quantitative data from aims 1-3 will be used to prepare final procedures for a future large-scale effectiveness trial R01 (aim 4).

Study Design


Attention Deficit Hyperactivity Disorder


Behaviorally Enhancing Adolescents' Mood in Schools, Usual Care


University of Maryland
College Park
United States




University of Maryland, College Park

Results (where available)

View Results


Published on BioPortfolio: 2019-10-01T07:55:03-0400

Clinical Trials [3713 Associated Clinical Trials listed on BioPortfolio]

Multi-Level Interventions for STD Prevention Among Adolescents

Sexually active adolescents between the ages of 10 and 19 are at extremely high risk for sexually transmitted diseases (STD), including HIV, and teen pregnancy.The overall goal of this res...

Enhancing IEPs of Children With ADHD Using Daily Report Cards

The purpose of this study are to determine the effectiveness of the daily report card (DRC) approach to supporting children with ADHD in special education in schools compared to a business...

The Measurement of Mood Variability and Sustained Attention in Women With Alcohol Dependence.

The purpose of this study is to measure daily mood changes and to find out whether these mood changes are related to the ability to maintain attention on a task. Problems with mood are mor...

Internet-based Program for Prevention and Early Intervention of Adolescent Depression

Background: Depression is prevalent and can have devastating effects on the life of adolescents. Computerized intervention programs for depression have shown positive results. There is les...

Correlates of Oral Human Papillomavirus Infection in Adolescents and Young Adults With Behaviorally Acquired HIV

The proposed study is a substudy of ATN 106 and a cross sectional study intended to be conducted at each of the AMTUs newly participating in ATN III. The intent is to enroll all youth with...

PubMed Articles [17854 Associated PubMed Articles listed on BioPortfolio]

Seven-day shared decision making for outpatients with first episode of mood disorders among university students: A randomized controlled trial.

Providing appropriate treatment to patients with a first episode of mood disorders is crucial for recovery from the disorders. Although shared decision making (SDM) has been proposed as a promising mo...

Effects of Brief Mood-Improving Interventions on Immunity: A Systematic Review and Meta-Analysis.

Positive mood has been associated with enhanced immune function. Interventions that improve mood could, therefore, provide a mechanism for optimising immune related health outcomes. Brief intervention...

Association Between Improvement in Baseline Mood and Long-Term Use of a Mindfulness and Meditation App: Observational Study.

The use of smartphone apps to monitor and deliver health care guidance and interventions has received considerable attention recently, particularly with regard to behavioral disorders, stress relief, ...

Effects of an Interdisciplinary Care Team on the Management of Alzheimer's Disease in China.

The current study aimed to evaluate the multidimensional effects of an interdisciplinary care team in patients with Alzheimer's disease (AD). A total of 129 patients with AD were randomly assigned to ...

Social health needs of Iranian male adolescents.

Background Adequate attention to adolescents' health is considered an investment for the future of any country. Adolescents face many social and cultural challenges when they enter a new stage of soci...

Medical and Biotech [MESH] Definitions

An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent.

Architecture, exterior and interior design, and construction of facilities other than hospitals, e.g., dental schools, medical schools, ambulatory care clinics, and specified units of health care facilities. The concept also includes architecture, design, and construction of specialized contained, controlled, or closed research environments including those of space labs and stations.

The hospital unit in which patients with respiratory conditions requiring special attention receive intensive medical care and surveillance.

The giving of attention to the special dental needs of the elderly for proper maintenance or treatment. The dental care may include the services provided by dental specialists.

Schools for children usually under five years of age.

More From BioPortfolio on "School-Based Depression Prevention for Adolescents With ADHD"

Quick Search

Relevant Topics

Pediatrics is the general medicine of childhood. Because of the developmental processes (psychological and physical) of childhood, the involvement of parents, and the social management of conditions at home and at school, pediatrics is a specialty. With ...

Psychiatry is the study of mental disorders and their diagnosis, management and prevention.  Conditions include schizophrenia, severe depression and panic disorders among others. There are pharmaceutical treatments as well as other therapies to help...

Searches Linking to this Trial