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Incidence, Risk Factors and Outcomes of Diaphragm Dysfunction After Lung Transplantation

2019-10-01 07:55:12 | BioPortfolio

Summary

The study is designed to characterize the changes in diaphragm function after lung transplantation.

Description

Diaphragm dysfunction (DD) is a well-known complication after lung transplantation. Patients with an injured and dysfunctional diaphragm have greater difficulty weaning from mechanical ventilation post-transplant - they become too weak to breathe. However, little is known about the pre-transplant predictive factors associated with diaphragm dysfunction . We have developed a new technique employing beside ultrasound to measure diaphragm thickness. This allows us to observe changes in diaphragm muscle structure and function.

The goal of the study is to determine whether pre-transplant diaphragm thickness and function are associated with diaphragmatic dysfunction after lung transplantation. This will help us to confirm the best way to avoid diaphragm injury and to understanding the meaning of diaphragm ultrasound images.

Study Design

Conditions

Diaphragm Injury

Intervention

Ultrasound, Respiratory function measurements

Location

Toronto General Hospital
Toronto
Canada

Status

Not yet recruiting

Source

University Health Network, Toronto

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-01T07:55:12-0400

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