Preoperative Excercise Training for Patients Undergoing Coronary Artery Bypass Graft Surgery

2019-10-08 08:47:42 | BioPortfolio


Patients (pts) with stable coronary artery disease (CAD) requiring coronary artery bypass graft surgery (CABG) may be physically inactive during the waiting period to avoid further risks. Aim of this study is to investigate the feasibility and safety of a preoperative aerobic exercise training in these pts during the waiting period and to analyze its effects on pre-, peri and postoperative outcomes


Pts with stable coronary artery disease (CAD) and indication for elective CABG will be prospectively randomized into a preoperative training group (TG) or a non active control group (CG). Pts in TG have to perform six sessions of aerobic endurance training within two weeks prior to CABG. The following investigations will be performed at baseline, one day before surgery and at the beginning and at the end of cardiac rehabilitation: a maximal symptom limited ergospirometry, assessment of endothelial function (analysing the reactive hyperaemic index (RHI) via a finger-tonometry), assessment of quality of life (QoL) using the MacNew Heart Disease Questionnaire, laboratory testing of ischemic and inflammatory Parameters. Baseline, peri- and postoperative characteristics will be collected.

Study Design


Coronary Artery Disease


Preoperative Exercise Training, Optimal medical therapy


Kerckhoff Klinik
Bad Nauheim




Kerckhoff Klinik

Results (where available)

View Results


Published on BioPortfolio: 2019-10-08T08:47:42-0400

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