Photoacoustic Imaging for Measuring Tumors and Normal Tissue in Patients With Head and Neck Cancer

2019-10-07 08:56:58 | BioPortfolio


This trial studies how well photoacoustic imaging works in measuring tumors and normal tissue in patients with head and neck cancer. Photoacoustic imaging (PAI) is a low-risk imaging method that provides information about the oxygenation of tissues using a combination of light and ultrasound techniques. This study may help doctors determine if PAI is correlated with clinical responses of both tumor (for example: shrinking, swelling or disappearing) and normal tissues (for example: skin redness, dry mouth, appearance of sores, healing of skin or mucosa). If there is a correlation with clinical responses, then doctors may develop PAI as method for measuring response to earlier treatment.



I. Define the feasibility of the current photoacoustic imaging (PAI) technology in head and neck (H&N) cancer patients.


I. Define the utility of the current PAI in H&N cancer patients.


PART I: Patients undergo PAI before the start of chemoradiation therapy, weekly during 7 weeks of chemoradiation, and again 3-4 months after completion of chemoradiation therapy.

PART II (CANCER-FREE WITH XEROSTOMIA): Patients undergo PAI at baseline, up to twice during acupuncture-like transcutaneous nerve stimulation (ALTENS) therapy, once after ALTENS, and at 3-6 months follow up.

Study Design


Head and Neck Carcinoma


Photoacoustic Imaging, Transcutaneous Acupoint Electrical Stimulation


Roswell Park Cancer Institute
New York
United States




Roswell Park Cancer Institute

Results (where available)

View Results


Published on BioPortfolio: 2019-10-07T08:56:58-0400

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