Oral Remimazolam With and Without Alcohol in Healthy Female Subjects

2019-10-08 08:47:30 | BioPortfolio


A Phase 1 Study to Determine the Single-dose Pharmacodynamics, Pharmacokinetics, and Safety and Tolerability of Remimazolam Following Oral Administration With and Without Alcohol in Healthy Female Subjects


Evaluating the potential for additive or synergistic effects of alcohol when coadministered with remimazolam. Female subjects were selected because they represent the population at greatest risk for victimization in drug-facilitated sexual assault. In addition, females have a slower ethanol metabolism, therefore, the effects of remimazolam, if coadministered with alcohol, may last longer. Hence, this population represents the worst-case scenario in evaluating the risk of remimazolam misuse in drug-facilitated assault.

Study Design


Safety Issues


Remimazolam, Alcohol


PRA Health Sciences (PRA) - Early Development Services
Salt Lake City
United States




Paion UK Ltd.

Results (where available)

View Results


Published on BioPortfolio: 2019-10-08T08:47:30-0400

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