DIEP Flap Perfusion Evaluated by DIRT and ICG-FA.
Summary
Patients selected for DIEP breast reconstruction were examined with preoperative CTA, Doppler Ultrasound, dynamic infrared thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) for perforator mapping. DIRT and ICG-FA were used to evaluate perfusion of selected perforators. Following anastomoses for the DIEP flap to internal mammary vessels , patency of the anastomosis was evaluated with DIRT and ICG-FA. Recorded images from all the modules were compared.
Description
Introduction:
'The primary aim of our study is to compare invasive and non-invasive techniques to select a dominant perforator when harvesting a DIEP-flap for autologous breast reconstruction.
The secondary aim is to compare Dynamic Infrared Thermography (DIRT) and Laser Fluorescence Angiography (LFA) of Indocyanine green (ICG) in order to see whether they could be useful in the early detection of insufficient perfusion following the microvascular anastomotic procedure in DIEP flaps.
Material and Method:
Patients selected for breast reconstruction with autologous tissue were examined with preoperative CTA and a handheld Doppler Ultrasound for perforator mapping. Thereafter visual images from same area was obtained with dynamic infraredeed thermography (DIRT) and Indocyanin green fluorescent angiography (ICG-FA) before and after dissection of the skin flap with preserved medial and lateral DIEP perforators. Reconstructed breasts with hemi-DIEP-flaps were intraoperatively evaluated with DIRT and LFA immediately after the completion and opening of the microvascular anastomosis.The recorded images from the different techniques were assesses in relation to clinical outcome.
.
Study Design
Conditions
Reconstructive Surgical Procedures
Intervention
Dynamic infrared thermography (DIRT) and indocyanine green fluorescence angiography (ICG-FA)
Location
Univesity Hospital of North Norway
Tromsø
Norway
9038
Status
Recruiting
Source
University Hospital of North Norway
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT04115995
- ClinicalTrials.gov processed this data on October 09, 2019
Published on BioPortfolio: 2019-10-10T09:39:40-0400
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Medical and Biotech [MESH] Definitions
Thermography
Measurement of the regional temperature of the body or an organ by infrared sensing devices, based on self-emanating infrared radiation.
Indocyanine Green
A tricarbocyanine dye that is used diagnostically in liver function tests and to determine blood volume and cardiac output.
Green Fluorescent Proteins
Protein analogs and derivatives of the Aequorea victoria green fluorescent protein that emit light (FLUORESCENCE) when excited with ULTRAVIOLET RAYS. They are used in REPORTER GENES in doing GENETIC TECHNIQUES. Numerous mutants have been made to emit other colors or be sensitive to pH.
Magnetic Resonance Angiography
Non-invasive method of vascular imaging and determination of internal anatomy without injection of contrast media or radiation exposure. The technique is used especially in CEREBRAL ANGIOGRAPHY as well as for studies of other vascular structures.
Infrared Rays
That portion of the electromagnetic spectrum usually sensed as heat. Infrared wavelengths are longer than those of visible light, extending into the microwave frequencies. They are used therapeutically as heat, and also to warm food in restaurants.
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