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Evalution of Hyaluronic Acid Pulpotomies in Primary Molars

2019-10-10 09:39:44 | BioPortfolio

Summary

In this study, 120 primary molar teeth from healthy children aged between 5 and 9 and who apply to Marmara University Faculty of Dentistry Department of Pediatric Dentistry will be subjected to pulpotomy treatments. After proper diagnosis of coronal pulpitis, the teeth will be assigned randomly to one of the 3 groups: 40 primary molars for formocrezol pulpotomy treatments, 40 primary molars for ferric sulfate treatments and 40 primary molars for 0.5% hyaluronic acid gel pulpotomy treatments. The tooth decay will be removed, the pulp will be amputated from the chamber of the pulp with a sharp excavator and one of the medicament will be applied to the orifice of the root canals. The cavity will be sealed tight with zinc oxide cement and stainless steel crowns. A single investigator will perform the procedure. The teeth will be followed clinically and radiographically at 1st, 3rd, 6th, 12th months.

Description

The aim of this study is to compare the efficacy of the materials used in pulpotomies, and to evaluate the success of hyaluronic gel over the formocrezol and/or ferric sulfate considered as the gold standard for this type of treatment.

Pulpotomy is an endodontic treatment method aiming to maintain primary molar affected from deep caries and acute pulpitis by removing the effected pulpal tissue, leaving the remaining root canal pulp and maintaining its vitality and function until the tooth exfoliates physiologically. In order to remain canals intact and uninflamed various dental materials are used according to treatment purposes; categorized into three groups as devitalizing, preventive and regenerative treatment.

1. Devitalization: Formocrezol, gluteraldehyde, electro-surgery

2. Protective : Ferric Sulfate, calcium hydroxide, mineral trioxide aggregate, lasers

3. Regenerative : Bone morphogenetic protein, Enriched collagen

The ideal agent or method for pulpotomy treatment of the primary teeth has not been determined yet but the earliest method of diluted formocresol is considered by many the gold standard. Formocrezol is a strong strain that fixes living tissues. It contains formaldehyde gas, organic structures, dentin channels and narrow side channels until the bacteria are also fixed. 10% formalin solution (14% formaldehyde) is used as a tissue fixative.

Ferric Sulfate an other material for pulpotomy is used in dentistry mainly as a hemostatic agent. It has several advantages over formocresol such as non-mutagenic property and keeping root canal pulp vital.

Hyaluronic acid gel, which is a new product as a pulpotomy material, has been used in dentistry as well as medicine for ... years. It is distributed widely in epitelial and connective tissues Medical uses include joint treatments, skin lotions for atopic dermatitis, cosmetic surgery etc. In dentistry, gingivitis, teething, dental surgery including implants and sinus lifting procedures and oral ulcers are main target for hyaluronic acid treatment. This study extends the use of hyaluronic acid to primary tooth endodontics.

In this study, 120 primary molar teeth from healthy children aged between 5 and 9 and who apply to Marmara University Faculty of Dentistry Department of Pediatric Dentistry will be subjected to pulpotomy treatments. After proper diagnosis of coronal pulpitis, local anestesia is administrated, the teeth will be assigned randomly to one of the 3 groups: 40 primary molars for formocrezol pulpotomy treatments, 40 primary molars for ferric sulfate treatments and 40 primary molars for 0.5% hyaluronic acid gel pulpotomy treatments. The tooth decay is removed, the roof of the pulp chamber is removed by joining the pulp horns with a bur cut. the coronal pulp is amputated from the chamber of the pulp with a sharp excavator and one or more cotton pellets is placed over the site and pressure is applied. When the hemostasis is insured, one of the medicament is applied to the orifice of the root canals. The cavity will be sealed tight with zinc oxide eugenol cement and a stainless steel crown is placed over the tooth for better tightness. A single investigator will perform the procedure. The teeth will be followed clinically and radiographically at 1, 3, 6, 12 months.

Study Design

Conditions

Pulpitis

Intervention

hyaluronic acid : gengigel teething, formocresol Buckley formula : Formacresol, ferric sulfate : ViscoStat

Location

Marmara University Faculty of Dentistry Department of Pediatric Dentistry
Istanbul
Turkey
34854

Status

Recruiting

Source

Marmara University

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-10T09:39:44-0400

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