Globus Pallidus Stimulation to Treat Insomnia
Summary
Researchers are to determine if turning on an additional unilateral DBS (deep brain stimulation) electrode with stimulation to the globus pallidus externa (GPe) region of the brain will improve insomnia (sleep).
Study Design
Conditions
Intervention
DEEP BRAIN STIMULATION
Location
Mayo Clinic in Florida
Jacksonville
Florida
United States
32224
Status
Recruiting
Source
Mayo Clinic
Results (where available)
Links
- Source: http://clinicaltrials.gov/show/NCT04116996
- ClinicalTrials.gov processed this data on October 10, 2019
Published on BioPortfolio: 2019-10-11T10:03:46-0400
Clinical Trials
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PubMed Articles
Deep brain stimulation in Parkinson's disease: A multicentric, long-term, observational pilot study.
The impact of deep brain stimulation (DBS) on cognitive and urinary disorders, falls, and eventually hospitalizations and mortality in Parkinson's disease (PD) is still debated.
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Interleaving stimulation in Parkinson's disease: interesting to whom?
Interleaving stimulation (ILS) is an available stimulation strategy that can help the physician manage more challenging cases of patients with deep brain stimulation (DBS) for Parkinson's disease. (PD...
The Six Sigma concept allows for the evaluation of quality changes after the implementation of new technical equipment or adjustment of perioperative procedures. Exemplarily, we applied this method fo...
Deep brain stimulation (DBS) for Parkinson's disease (PD) has been applied to clinic for approximately 30 years. The goal of this review is to explore the similarities and differences between "awake...
Medical and Biotech [MESH] Definitions
Deep Brain Stimulation
Therapy for MOVEMENT DISORDERS, especially PARKINSON DISEASE, that applies electricity via stereotactic implantation of ELECTRODES in specific areas of the BRAIN such as the THALAMUS. The electrodes are attached to a neurostimulator placed subcutaneously.
Self Stimulation
Stimulation of the brain, which is self-administered. The stimulation may result in negative or positive reinforcement.
Parkinson Disease Associated Proteins
Proteins associated with sporadic or familial cases of PARKINSON DISEASE.
Mptp Poisoning
A condition caused by the neurotoxin MPTP which causes selective destruction of nigrostriatal dopaminergic neurons. Clinical features include irreversible parkinsonian signs including rigidity and bradykinesia (PARKINSON DISEASE, SECONDARY). MPTP toxicity is also used as an animal model for the study of PARKINSON DISEASE. (Adams et al., Principles of Neurology, 6th ed, p1072; Neurology 1986 Feb;36(2):250-8)
Parkinsonian Disorders
A group of disorders which feature impaired motor control characterized by bradykinesia, MUSCLE RIGIDITY; TREMOR; and postural instability. Parkinsonian diseases are generally divided into primary parkinsonism (see PARKINSON DISEASE), secondary parkinsonism (see PARKINSON DISEASE, SECONDARY) and inherited forms. These conditions are associated with dysfunction of dopaminergic or closely related motor integration neuronal pathways in the BASAL GANGLIA.
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