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Melatonin for Prevention of Post Stroke Delirium

2019-10-16 10:39:33 | BioPortfolio

Summary

Post stroke delirium is prevalent in 10-30% of all stroke patients. We aimed to investigate wether Melatonin 2mg may prevent post stroke delirium.

Study Design

Conditions

Post Stroke Delirium

Intervention

Melatonin

Location

Klinik für Neurologie
Tübingen
BW
Germany
72076

Status

Recruiting

Source

University Hospital Tuebingen

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-16T10:39:33-0400

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PubMed Articles [6894 Associated PubMed Articles listed on BioPortfolio]

The effect of melatonin on delirium in hospitalised patients: A systematic review and meta-analyses with trial sequential analysis.

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Delirium is a very common neurobehavioral complication after stroke, but its influence on long-term outcome is not well characterized. The objective of the study was to determine the prognostic signif...

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Medical and Biotech [MESH] Definitions

A biogenic amine that is found in animals and plants. In mammals, melatonin is produced by the PINEAL GLAND. Its secretion increases in darkness and decreases during exposure to light. Melatonin is implicated in the regulation of SLEEP, mood, and REPRODUCTION. Melatonin is also an effective antioxidant.

A family of G-protein-coupled receptors that are specific for and mediate the effects of MELATONIN. Activation of melatonin receptors has been associated with decreased intracellular CYCLIC AMP and increased hydrolysis of PHOSPHOINOSITIDES.

A form of DELIRIUM which occurs after GENERAL ANESTHESIA.

A melatonin receptor subtype primarily found expressed in the BRAIN and RETINA.

A melatonin receptor subtype that is primarily found in the HYPOTHALAMUS and in the KIDNEY.

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