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Euphrasia Eye Drops in Preterm Infants With First Signs of Congestion of Nasolacrimal Duct

2019-10-14 10:28:48 | BioPortfolio

Summary

Congenital nasolacrimal duct obstruction (CNLDO) occurs in approximately 10 to 20% of all term newborns, and is the most common cause of persistent tearing and ocular discharge in children. CNLDO causes symptoms in up to 6% of children during the first year of life. The first clinical signs appear during the first month of life in 95% of cases and usually consist of tearing and debris on the eyelashes ("mattering"). Mucopurulent eye discharge occurs commonly in infants with CNLDO and, in the absence of other signs of infection, suggests bacterial overgrowth in the stagnant tear pool of the lacrimal sac.

This study investigates whether early administration of Euphrasia eye drops (Weleda AG, Arlesheim) in preterm neonates presenting with first ocular discharge with or without tearing and reddened eye fosters the resolution of the ocular discharge and reduces the need for topical antibiotic therapy.

Study Design

Conditions

Congenita Nasolacrimal Duct Obstruction

Intervention

Euphrasia Officinalis Preparation, Placebo

Location

Department of Neonatology, Children University Hospital of Bern
Bern
Switzerland
3010

Status

Completed

Source

University of Bern

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-14T10:28:48-0400

Clinical Trials [733 Associated Clinical Trials listed on BioPortfolio]

Study of Surgical Procedures for Treatment of Persistent Nasolacrimal Duct Obstruction in Children < 4 Years Old

The purpose of this study is: - To report the success proportions for the treatment of persistent nasolacrimal duct obstruction for three surgical procedures: balloon catheter dil...

Are Corneal Epithelial Defects Related to Changes in Ocular Bacterial Flora in Patients With ANLDO

Comparison between patients with nasolacrimal duct obstruction and healthy patients and the influence of their bacterial flora on the corneal epithelium.

Comparative Study of Two Operations for Lacrimal Duct Obstruction

To compare the clinical effects between the silicone nasolacrimal intubation under nasaendoscopy and dacryocystorhinostomy on patients with lacrimal duct obstruction.

Endoscopy Assisted Probing Versus Simple Probing in Primary Congenital Nasolacrimal Duct Obstruction

The aim of this study is to compare results of endoscopy assisted nasolacrimal probing with the standard simple probing in cases with congenital nasolacrimal duct obstruction . Furthermore...

Immediate Office Probing vs Deferred Facility Probing for Nasolacrimal Duct Obstruction in Children 6 to <10 Months Old

The purpose of this study is: To determine the cost-effectiveness of treating NLDO using immediate office probing compared with deferred probing in a facility setting. As part of the prim...

PubMed Articles [3704 Associated PubMed Articles listed on BioPortfolio]

Risk Factors for Poor Surgical Outcome of Pediatric Nasolacrimal Duct Obstruction.

To determine whether there are common factors that may help predict if a child is at a higher risk for surgical failure for nasolacrimal duct obstruction.

Amblyopia risk factors in congenital nasolacrimal duct obstruction: A longitudinal case-control study.

To investigate longitudinal changes in risk factors for amblyopia in children treated with congenital nasolacrimal duct obstruction (CNLDO).

Effect of Probing in Congenital Nasolacrimal Duct Obstruction in Children Older Than 2 Years.

To determine the effect of probing for congenital nasolacrimal duct obstruction in children older than 2 years.

Dacryoendoscopic assisted nasolacrimal intubation in an Australian population.

Epiphora is a common presenting symptom of nasolacrimal obstruction. Determining the level of nasolacrimal obstruction will influence the choice of management and can be aided by lacrimal imaging. Thi...

The Role of Bacterial Etiology in the Tear Duct Infections Secondary to Congenital Nasolacrimal Duct Obstructions.

To define the microbiological features of dacryocystitis in childhood.

Medical and Biotech [MESH] Definitions

Interference with the secretion of tears by the lacrimal glands. Obstruction of the lacrimal sac or nasolacrimal duct causing acute or chronic inflammation of the lacrimal sac (DACRYOCYSTITIS). It is caused also in infants by failure of the nasolacrimal duct to open into the inferior meatus and occurs about the third week of life. In adults occlusion may occur spontaneously or after injury or nasal disease. (Newell, Ophthalmology: Principles and Concepts, 7th ed, p250)

A tubular duct that conveys TEARS from the LACRIMAL GLAND to the nose.

Surgical fistulization of the lacrimal sac for external drainage of an obstructed nasolacrimal duct.

A group of inherited ectodermal dysplasias whose most prominent clinical feature is hypertrophic nail dystrophy resulting in PACHYONYCHIA. Several specific subtypes of pachyonychia congenita have been associated with mutations in genes that encode KERATINS.

The largest bile duct. It is formed by the junction of the CYSTIC DUCT and the COMMON HEPATIC DUCT.

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