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This study will determine the level of functional gain, below the injury for voluntary control of movements, and recovery standing and stepping function as a result of activation of spinal circuits with scES in humans with severe paralysis. Training will consist of practicing stepping, standing and voluntary movements in the presence of specific scES configurations designed specific for stepping (Step-scES), specific for standing (Stand-scES) and for the voluntary movements of the legs and trunk (Vol-scES). Ability to step, stand, move voluntarily, as well as cardiovascular, respiratory, bladder, bowel and sexual function will be assessed in these individuals with chronic severe spinal cord injury.
Spinal Cord Injuries
Standing and Stepping, Standing, Stepping and Voluntary Movement with spinal cord Epidural Stimulation
University of Louisville
University of Louisville
Published on BioPortfolio: 2019-10-17T11:03:45-0400
Spinal cord neural circuitry exists in the lumbar enlargement that makes it possible to stand and create synergistic, rhythmic stepping activity in the lower limbs. In the past 20 years, c...
Upright-working has been proven to benefit health by combating the negative effects of physical inactivity. However, long-term commitment to static standing regimens may be limited due to ...
The purpose of this study was to examine the influence of cane use on the movement, kinetics, and associated attentional demands of performing a voluntary forward stepping movement in pati...
The investigators propose to understand the role of lumbosacral spinal cord epidural stimulation (scES) in recovery of autonomic nervous system function, voluntary movement, and standing i...
- Does stepping training with or without external feedback change functional ability of ambulatory patients with iSCI immediately after training? - Are there significant differen...
This cross-sectional study examined the interrelationships between workplace movement (sitting, standing, and stepping), availability of discussion space, and face-to-face (FTF) interactions between w...
Stepping is critical for responding to perturbations, whether externally induced or self-initiated. Falls post-stroke is equally likely to happen from either mechanism. The objective of the study was,...
Orthostatic tremor (OT) is a rare movement disorder characterized by a fast tremor (13-18 Hz) in the lower extremities during stance. Patients with OT typically complain of instability while standing/...
Various interventions, such as standing intermittently with one leg on a footrest, have been suggested to prevent low back pain (LBP) development during prolonged standing. To assess this standing int...
Standing is commonly recommended to reduce sedentary behavior in the workplace; however, constrained prolonged standing has also been linked to musculoskeletal symptoms, such as low back pain (LBP). L...
A significant drop in BLOOD PRESSURE after assuming a standing position. Orthostatic hypotension is a finding, and defined as a 20-mm Hg decrease in systolic pressure or a 10-mm Hg decrease in diastolic pressure 3 minutes after the person has risen from supine to standing. Symptoms generally include DIZZINESS, blurred vision, and SYNCOPE.
A POSTURE in which an ideal body mass distribution is achieved. Postural balance provides the body carriage stability and conditions for normal functions in stationary position or in movement, such as sitting, standing, or walking.
Medical procedures and prescriptions regarding treatment of a patient that can be exercised by other health care personnel when predetermined conditions have been met.
Educational programs designed to inform individuals of recent advances in their particular field of interest. They do not lead to any formal advanced standing.
The distance from the sole to the crown of the head with body standing on a flat surface and fully extended.
Cardiovascular disease (CVD)
Acute Coronary Syndromes (ACS) Blood Cardiovascular Dialysis Hypertension Stent Stroke Vascular Cardiovascular disease (CVD) includes all the diseases of the heart and circulation including coronary heart disease (angina...
Asthma COPD Cystic Fibrosis Pneumonia Pulmonary Medicine Respiratory Respiratory tract infections (RTIs) are any infection of the sinuses, throat, airways or lungs. They're usually caused by viruses, but they can also ...
Non-invasive bladder cancer is a cancer that is only in the inner lining of the bladder. Invasive bladder cancer is cancer that has spread into the deeper walls of the bladder. When the cancer has spread outside the bladder to other parts of the body, th...