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rTMS to Enhance Cognitive Performance and Promote Resilience

2019-10-16 10:39:20 | BioPortfolio

Summary

The purpose of this study is to determine the most effective dose of brief, non-invasive brain stimulation (repetitive transcranial magnetic stimulation, rTMS) for improving cognitive functions such as attention and memory as well as to improve the ability to recover from stressful situations (stress resilience).

Description

Repetitive transcranial magnetic stimulation (rTMS) works by rapidly turning a focused magnetic field on-and-off repeatedly over your head, which passes directly through your hair, scalp, and skull and onto your brain, and can temporarily increase brain activity under the magnetic field. Repetitive transcranial magnetic stimulation (rTMS) is an FDA approved treatment for depression, and is used commonly to treat people for their depression. The rTMS treatment regime used in this study is different from the FDA approved treatment because you will receive up to ten treatments per day over five days instead of the FDA approved rTMS treatment regime of 25 treatments over 25 days. This sort of accelerated or high dose protocol has been shown to be safe and effective in the treatment of depression. We are hoping to find out if this treatment can be used as a treatment for improving cognitive function and stress resilience.

Study Design

Conditions

Cognition

Intervention

rTMS

Location

Medical University of South Carolina
Charleston
South Carolina
United States
29401-5799

Status

Recruiting

Source

Medical University of South Carolina

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-16T10:39:20-0400

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PubMed Articles [1154 Associated PubMed Articles listed on BioPortfolio]

Effects of Online Repetitive Transcranial Magnetic Stimulation (rTMS) on Cognitive Processing: A Meta-Analysis and Recommendations for Future Studies.

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Low-frequency rTMS is better tolerated than high-frequency rTMS in healthy people: Empirical evidence from a single session study.

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Potential predictors of depressive relapse following repetitive Transcranial Magnetic Stimulation: A systematic review.

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Simultaneously applying cathodal tDCS with low frequency rTMS at the motor cortex boosts inhibitory aftereffects.

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Medical and Biotech [MESH] Definitions

Measures of spatial cognition and memory.

Intellectual or mental process whereby an organism becomes aware of or obtains knowledge.

Disturbances in the mental process related to thinking, reasoning, and judgment.

A mechanism of information stimulus and response that may control subsequent behavior, cognition, perception, or performance. (From APA Thesaurus of Psychological Index Terms, 8th ed.)

Motivational state produced by inconsistencies between simultaneously held cognitions or between a cognition and behavior; e.g., smoking enjoyment and believing smoking is harmful are dissonant.

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