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Clinical Relevance of the Reverse Lipopolysaccharide Transport Pathway in Patients With Acute Peritonitis

2019-10-21 12:45:40 | BioPortfolio

Summary

When there is infection in the intra-abdominal area, bacteria secrete toxins that are absorbed by the peritoneum. These toxins then bind to lipoproteins (which carry cholesterol in the blood) and are eliminated by the liver. Phospholipid transfer protein (PLTP) is a protein that facilitates the binding of bacterial toxins to lipoproteins and thus their elimination.

The objective of this study is to study the relationship between PLTP and the elimination of bacterial toxins in humans. A better understanding of the elimination of these toxins will lead to a better understanding of the disease. The ultimate objective is to improve the management of intra-abdominal infections.

Study Design

Conditions

Peritonitis

Intervention

blood samples

Location

Chu Dijon Bourogne
Dijon
France
21000

Status

Not yet recruiting

Source

Centre Hospitalier Universitaire Dijon

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-21T12:45:40-0400

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