Impact of AIT on Allergic Rhinitis and Asthma

2019-10-18 11:21:36 | BioPortfolio


The study will assess the effectiveness of AIT treatment in real clinical practice in Germany.


Allergic rhinitis (AR) affects 23-30% of the European population and is associated with a major burden on public health. AR and asthma frequently coexist, and may both be caused by allergen exposure. While the efficacy of AIT, i.e. reduce symptoms and medication use in patients with AR and asthma, has been demonstrated in several randomized clinical trials, little is known about the use and effectiveness of AIT in real world clinical practice.

This study is a retrospective database study that uses real-world data from Germany. The study population consists of AR patients with and without asthma treated with AIT and matched controls not treated with AIT. Information about the patients and treatments will be obtained from the 'BKK German Sickness Fund Database' from 2007 until 2017.

Study Design




Allergy immunotherapy (AIT)


ALK Abelló


Active, not recruiting


ALK-Abelló A/S

Results (where available)

View Results


Published on BioPortfolio: 2019-10-18T11:21:36-0400

Clinical Trials [599 Associated Clinical Trials listed on BioPortfolio]

Penicillin Allergy Testing and Resensitization Rate

Penicillin is one of the earliest discovered antibiotics and a drug of choice for several infections. Up to 10 to 20% of all patients in clinical trial are labeled as penicillin allergic. ...

De-labeling of Patients With False Diagnosis of Penicillin Allergy

The purpose of this study is to estimate the prevalence of penicillin allergy, evaluate the diagnostic value of the allergologic work-up used in the study, and the health effects of penici...

The Influence of Early and Continuous Exposure of Infants to Cow's Milk Formula on the Prevention of Milk Allergy

Cow's milk protein (CMP) allergy is one of the most common food allergies and potentially a fatal one. Early feeding with CMP has been considered in the past as a risk factor for developme...

Anti-TSLP (AMG 157) Plus Antigen-Specific Immunotherapy for Induction of Tolerance in Individuals With Cat Allergy

The purpose of this research study is to find out if cat allergy shots with combination with AMG 157, an experimental medication, will help the cat allergy shots work after just one year o...

Effectiveness of Cat-PAD to Treat Cat Allergy in Cat Allergic Subjects

Cat allergy is an increasingly prevalent condition, affecting 10-15% of patients with allergic rhinoconjunctivitis and/or asthma. Cat-PAD is a novel, synthetic, allergen-derived peptide d...

PubMed Articles [2097 Associated PubMed Articles listed on BioPortfolio]

Food and drug allergy, and anaphylaxis in EAACI journals (2018).

The European Academy of Allergy and Clinical Immunology (EAACI) supports three journals: "Allergy", "Pediatric Allergy and Immunology (PAI)" and "Clinical and Translational Allergy (CTA)". One of the ...

Effectiveness and Safety of Double-Blind, Placebo-Controlled, Low-Dose Oral Immunotherapy with Low Allergen Egg-Containing Cookies for Severe Hen's Egg Allergy: A Single-Center Analysis.

The usefulness of low-dose oral immunotherapy (OIT) for the treatment of egg allergy has been unclear.

Exclusive Bee Venom Allergy: Risk Factors and Outcome of Immunotherapy.

Venom immunotherapy (VIT) is considered to be the gold-standard treatment for patients with Hymenoptera venom allergy. Data regarding VIT in bee venom (BV) allergic patients are scarce.

Allergy immunotherapy: Who, what, when...and how safe?

The evidence-based answers to these and other questions will help you to update your knowledge of allergy immunotherapy.

Oral Immunotherapy for Multiple Foods in a Pediatric Allergy Clinic Setting.

The rising incidence of pediatric food allergy results in significant health care burden and family stress. Oral immunotherapy (OIT) has been shown to induce tolerance to peanut, milk and egg. OIT for...

Medical and Biotech [MESH] Definitions

A method of treating an ALLERGY by administering ALLERGENS, in liquid formulation or tablets, to the ORAL MUCOSA under the tongue.

A medical specialty concerned with the hypersensitivity of the individual to foreign substances and protection from the resultant infection or disorder.

A selective histamine H1-receptor antagonist devoid of central nervous system depressant activity. The drug was used for ALLERGY but withdrawn due to causing LONG QT SYNDROME.

A vascular reaction of the skin characterized by erythema and wheal formation due to localized increase of vascular permeability. The causative mechanism may be allergy, infection, or stress.

The main glucocorticoid secreted by the ADRENAL CORTEX. Its synthetic counterpart is used, either as an injection or topically, in the treatment of inflammation, allergy, collagen diseases, asthma, adrenocortical deficiency, shock, and some neoplastic conditions.

More From BioPortfolio on "Impact of AIT on Allergic Rhinitis and Asthma"

Quick Search

Relevant Topics

The term allergy is used to describe a response, within the body, to a substance, which is not necessarily harmful in itself, but results in an immune response and a reaction that causes symptoms and disease in a predisposed person, which in turn can cau...

Public Health
Alternative Medicine Cleft Palate Complementary & Alternative Medicine Congenital Diseases Dentistry Ear Nose & Throat Food Safety Geriatrics Healthcare Hearing Medical Devices MRSA Muscular Dyst...

Asthma is caused by inflammation of small tubes, called bronchi, which carry air in and out of the lungs. If you have asthma, the bronchi will be inflamed and more sensitive than normal.  When you come into contact with something that irritates your...

Searches Linking to this Trial