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Oral Dydrogesterone vs. Micronized Vaginal Progesterone for Luteal Phase Support in Frozen-thawed Embryo Transfer Cycles

2019-10-18 11:21:43 | BioPortfolio

Summary

The aim of this randomized controlled trial is to compare the efficacy of oral dydrogesterone vs. micronized vaginal progesterone for luteal phase support in frozen-thawed embryo transfer cycles.

Study Design

Conditions

Infertility, Female

Intervention

Dydrogesterone 10 MG Oral Tablet, Progesterone Vaginal Gel [Crinone]

Location

Memorial Şişli Hospital
Istanbul
Şişli
Turkey
34385

Status

Recruiting

Source

Memorial Sisli Hospital, Istanbul

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-18T11:21:43-0400

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Medical and Biotech [MESH] Definitions

A synthetic progestational hormone with no androgenic or estrogenic properties. Unlike many other progestational compounds, dydrogesterone produces no increase in temperature and does not inhibit OVULATION.

Diminished or absent ability of a female to achieve conception.

Specific proteins found in or on cells of progesterone target tissues that specifically combine with progesterone. The cytosol progesterone-receptor complex then associates with the nucleic acids to initiate protein synthesis. There are two kinds of progesterone receptors, A and B. Both are induced by estrogen and have short half-lives.

Steroidal compounds related to PROGESTERONE, the major mammalian progestational hormone. Progesterone congeners include important progesterone precursors in the biosynthetic pathways, metabolites, derivatives, and synthetic steroids with progestational activities.

The reproductive organ (GONADS) in female animals. In vertebrates, the ovary contains two functional parts: the OVARIAN FOLLICLE for the production of female germ cells (OOGENESIS); and the endocrine cells (GRANULOSA CELLS; THECA CELLS; and LUTEAL CELLS) for the production of ESTROGENS and PROGESTERONE.

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