Topics

Multimodal Ophthalmic Imaging

2019-10-21 12:45:21 | BioPortfolio

Summary

Knowledge of the pathogenesis of ocular conditions, a leading cause of blindness, has benefited greatly from recent advances in ophthalmic imaging. However, current clinical imaging systems are limited in resolution, speed, or access to certain structures of the eye.

The use of a high-resolution imaging system improves the resolution of ophthalmoscopes by several orders of magnitude, allowing the visualization of many microstructures of the eye: photoreceptors, vessels, nerve bundles in the retina, cells and nerves in the cornea.

The use of a high-speed acquisition imaging system makes it possible to detect functional measurements such as the speed of blood flow. The combination of data from multiple imaging systems to obtain multimodal information is of great importance for improving the understanding of structural changes in the eye during a disease.

The purpose of this project is to observe structures that are not detectable with routinely used systems.

Description

The goal of the project is the capture and analysis of images with the IMA-MODE systems, in order to evaluate the performance of these systems compared to the existing clinical imaging devices used at the National Hospital of Ophthalmology.

This project should identify the best techniques to image the eye, and select the most promising techniques to evolve towards a possible development of a medical device.

Study Design

Conditions

Retinitis Pigmentosa

Intervention

High-resolution retinal imaging through adaptive optics, High-resolution retinal imaging through holographic systems

Location

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts
Paris
France
75012

Status

Recruiting

Source

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-21T12:45:21-0400

Clinical Trials [5388 Associated Clinical Trials listed on BioPortfolio]

Retinal Imaging in Patients With Inherited Retinal Degenerations

The purpose of this study is to determine whether the structure and function of the human retina can be studied with high resolution in patients with inherited retinal degenerations using ...

High Resolution Retina Imaging

To increase the clinical experience of using the rtx1 camera in various retinal disorders and to follow the evolution of structural alterations during retinal diseases using adaptive optic...

Adaptive Optics in PVR

The purpose of this study is to investigate the loss of retinal cells following retinal detachment surgery using an imaging device called an adaptive optics camera. The retina is a thin la...

Advanced OCT and Adaptive Optics Imaging in Retinal Disease (The ACAD Study)

The objectives of this study include using the new technology of SS-OCT (swept source optical coherence tomography) to evaluate morphological abnormalities of the vitreous, retina and chor...

Snapshot Camera for AMD

This study proposes to use a new instrument (AO-OCT/AF: adaptive optics - optical coherence tomography/autofluorescence) combined with a data processing method to image the retinal pigment...

PubMed Articles [39618 Associated PubMed Articles listed on BioPortfolio]

Coextensive synchronized SLO-OCT with adaptive optics for human retinal imaging.

We describe the details of a multimodal retinal imaging system which combines adaptive optics (AO) with an integrated scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT) imaging...

Higher adaptive optics loop rate enhances axial resolution in nonconfocal ophthalmoscopes.

In this Letter, we propose a way to better understand the impact of dynamic ocular aberrations in the axial resolution of nonconfocal adaptive optics (AO) ophthalmoscopes via a simulation of the 3D PS...

Live Imaging of Mouse Retinal Slices.

Live fluorescent microscopy of whole-mount rodent retinal explants has proved to be extremely valuable for understanding dynamic events during retinogenesis. However, to obtain three-dimensional image...

Optical design of the High Resolution Imaging Channel of SIMBIO-SYS.

This paper describes the optical design of the High Resolution Imaging Channel (HRIC), which is part of the spectrometers and imagers for the Mercury Planetary Orbiter BepiColombo Integrated Observato...

Photoreceptor Degeneration is Correlated With the Deterioration of Macular Retinal Sensitivity in High Myopia.

To investigate structural changes in the retinal outer layers and choroid using adaptive optics (AO) and optical coherence tomography (OCT) in eyes with myopia, and to correlate the changes with decre...

Medical and Biotech [MESH] Definitions

High resolution imaging techniques that allow visualization of individual molecules of proteins, lipids, or nucleic acids within cells or tissues.

Magnetic resonance imaging diagnostic technique which uses fluorine-19 perfluorocarbon probes and contrast agents for high resolution image detection and quantitation.

Nanometer-sized tubes composed mainly of CARBON. Such nanotubes are used as probes for high-resolution structural and chemical imaging of biomolecules with ATOMIC FORCE MICROSCOPY.

Mild to fulminant necrotizing vaso-occlusive retinitis associated with a high incidence of retinal detachment and poor vision outcome.

Liquid chromatographic techniques which feature high inlet pressures, high sensitivity, and high speed.

More From BioPortfolio on "Multimodal Ophthalmic Imaging"

Quick Search

Relevant Topics

Neurology - Central Nervous System (CNS)
Alzheimer's Disease Anesthesia Anxiety Disorders Autism Bipolar Disorders Dementia Epilepsy Multiple Sclerosis (MS) Neurology Pain Parkinson's Disease Sleep Disorders Neurology is the branch of me...

Ophthalmology
Ophthalmology is the branch of medicine that is devoted to the study and treatment of eye diseases. As well as mild visual defects correctable by lenses, ophthalmology is concerned with glaucoma, uveitis and other serious conditions affecting the eye, ...

Mergers & Acquisitions
Commercial and market reports on mergers and acquisitions in the biotechnology, pharmaceutical, medical device and life-science industries. Mergers and acquisitions (abbreviated M&A;) is an aspect of corporate strategy, corporate finance and manageme...


Searches Linking to this Trial