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The proposed study is a randomized controlled trial among 180 patients with acute ischemic stroke and mod/severe OSA diagnosed by ambulatory PSG comparing PAP treatment with usual care concerning the primary outcome of functional recovery.
This study has 3 main aims and an additional exploratory aim.
Specific aim 2: Determine whether acute vs. subacute initiation of PAP in ischemic stroke results in greater improvement in post-stroke outcomes (stroke severity, symptoms, stroke recovery, quality of life).
Specific Aim 3: Conduct in-depth qualitative interviews with 25-30 stroke patients, family members, and acute care providers to elicit their experience with PAP use, including factors that influence adherence.
Exploratory aim: Evaluate whether polysomnographic measures have prognostic utility in understanding the variability in stroke recovery.
Published on BioPortfolio: 2019-10-23T13:11:49-0400
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Restoration of functions to the maximum degree possible in a person or persons suffering from a stroke.
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