Identifying Most Effective Treatment Strategies to Control Arterial Hypertension in Sub-Saharan Africa

2019-10-23 13:11:54 | BioPortfolio


This study is to compare the effectiveness of three different antihypertensive treatment strategies for reaching a target blood pressure (clinic BP) of /=65years of Age in HIV-positive and HIV-negative patients with uncomplicated arterial hypertension in rural Tanzania and Lesotho.

Study Design


Arterial Hypertension


dual combination, triple combination, Standard of care


SolidarMed Lesotho, Mokhotlong Government Hospital


Not yet recruiting


University Hospital, Basel, Switzerland

Results (where available)

View Results


Published on BioPortfolio: 2019-10-23T13:11:54-0400

Clinical Trials [7248 Associated Clinical Trials listed on BioPortfolio]

The Use of TRIple Fixed-dose COmbination in the Treatment of arteriaL Hypertension: Opportunity for Effective BP Control With cOmbined Antihypertensive theRapy

The use of TRIple fixed-dose COmbination in the treatment of arteriaL hypertension: opportunity for effective BP control with cOmbined antihypertensive therapy. The main aim of this study...

The Efficacy and Safety of Initial Triple Versus Initial Dual Oral Combination Therapy in Patients With Newly Diagnosed Pulmonary Arterial Hypertension

The objective of this clinical trial is to compare the efficacy and safety of an initial triple oral treatment regimen (macitentan, tadalafil, selexipag) versus an initial dual oral treatm...

Study to Compare Triple Therapy (Oral Treprostinil, Ambrisentan, and Tadalafil) With Dual Therapy (Ambrisentan, Tadalafil, and Placebo) in Subjects With Pulmonary Arterial Hypertension

This is a multicenter, randomized (2:1 oral treprostinil: placebo), double-blind, placebo-controlled study in subjects with Pulmonary Arterial Hypertension (PAH) who are currently receivin...

Upfront Combination Pulmonary Arterial Hypertension Therapy

To evaluate the safety and efficacy of first-line combination therapy using riociguat with ambrisentan in patients with Pulmonary Arterial Hypertension (PAH).

Early Therapy of Pulmonary Arterial Hypertension

Exercise-induced increase of the pulmonary arterial pressure may be an early sign of pulmonary arterial hypertension. It has been shown that patients with normal pulmonary arterial pressur...

PubMed Articles [19665 Associated PubMed Articles listed on BioPortfolio]

Combination Therapy with Oral Treprostinil for Pulmonary Arterial Hypertension: A Double-Blind, Placebo-Controlled Study.

Oral treprostinil improves exercise capacity in patients with pulmonary arterial hypertension (PAH), but the effect on clinical outcomes was unknown.

Risk reduction and right heart reverse remodeling by upfront triple combination therapy in pulmonary arterial hypertension.

Combinations of therapies are currently recommended for the most severely ill patients with pulmonary arterial hypertension (PAH), and excellent results have been reported with triple upfront combinat...

Patients With Cystic Fibrosis Have New Triple-Drug Combination.

Pulmonary Hypertension: Diagnostics, Classification and Therapy.

Pulmonary hypertension is a chronic, incurable disease with poor prognosis. The therapeutic aim is a stabilization of patients showing signs of right heart failure as well as disease progression. A pu...

Prospective Randomised Controlled Trial Comparing Treatment Efficacy and Tolerance of Picosecond Alexandrite Laser with a Diffractive Lens Array and Triple Combination Cream in Female Asian Patients with Melasma.

Recent evidence suggests melasma to be a photoaging disorder. Triple combination creams (TCC; fluocinolone acetonide 0.01%, hydroquinone 4%, and tretinoin 0.05%) remain the gold standard treatment. Pi...

Medical and Biotech [MESH] Definitions

A pharmaceutical preparation of amlodipine and valsartan that is used for the treatment of HYPERTENSION.

A pharmaceutical preparation of amlodipine besylate and olmesartan medoxomil that combines ANGIOTENSIN II TYPE I RECEPTOR ANTAGONIST and CALCIUM CHANNEL BLOCKER activities. It is used in the management of HYPERTENSION.

Inhibitor or Reverse Transcriptases or of RNA-dIrected DNA polymerase.

Therapy with two or more separate preparations given for a combined effect.

Common occlusive arterial disease which is caused by ATHEROSCLEROSIS. It is characterized by lesions in the innermost layer (ARTERIAL INTIMA) of arteries including the AORTA and its branches to the extremities. Risk factors include smoking, HYPERLIPIDEMIA, and HYPERTENSION.

More From BioPortfolio on "Identifying Most Effective Treatment Strategies to Control Arterial Hypertension in Sub-Saharan Africa"

Quick Search

Relevant Topics

Human Immuno Deficiency Virus (HIV)
Human Immunodeficiency Virus (HIV), the causative agent of AIDS. The Human Immunodeficiency Virus, more commonly known as HIV, is a member of the lentivirus sub-set of the retrovirus family of pathogens. It causes AIDS, or Acquired Immuno Deficiency Sy...

Cardiology is a specialty of internal medicine.  Cardiac electrophysiology : Study of the electrical properties and conduction diseases of the heart. Echocardiography : The use of ultrasound to study the mechanical function/physics of the h...

Searches Linking to this Trial