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A Trial to Compare Ibrutinib Versus Lenalidomide in Combination With MRE-chemotherapy for Adult Patients With Recurrent/Refractory Primary Central Nervous System Lymphoma (PCNSL)

2019-10-23 13:11:55 | BioPortfolio

Summary

This is a open-label,multicenter, randomised, three-arm, phase II efficacy and safety study of ibrutinib in combination with MRE(methotrexate,rituximab,etoposide)-chemotherapy versus lenalidomide in combination with MRE-chemotherapy given to adult patients who have recurrent/refractory primary central nervous system lymphoma (PCNSL)

Study Design

Conditions

Recurrent/RefractoryPrimary Central Nervous System Lymphoma (PCNSL)

Intervention

Ibrutinib, Lenalidomide, Methotrexate, Rituximab, Etoposide, PEGylated recombinant human granulocyte colony

Location

Department of Hematology, the Second Affiliated Hospital, Zhejiang University School of Medicine
Hangzhou
China/Zhejiang Province
China
310009

Status

Recruiting

Source

Second Affiliated Hospital, School of Medicine, Zhejiang University

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-23T13:11:55-0400

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