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Intratympanic Steroids for Sudden Hearing Loss

2019-10-23 13:11:55 | BioPortfolio

Summary

For patients with sudden hearing loss, the initial treatment is not usually effective. We use Dexamethasone or Methylprednisolone to be an Intratympanic steroid administration as a salvage treatment. An randomized, double-blind, multi-center study is designed to find the difference between Dexamethasone or Methylprednisolone.

Study Design

Conditions

Dexamethasone or Methylprednisolone; Sudden Hearing Loss; Intratympanic Steroid

Intervention

Dexamethasone or Methylprednisolone

Status

Not yet recruiting

Source

Second Affiliated Hospital, School of Medicine, Zhejiang University

Results (where available)

View Results

Links

Published on BioPortfolio: 2019-10-23T13:11:55-0400

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PubMed Articles [6145 Associated PubMed Articles listed on BioPortfolio]

Analysis of prognostic factors in patients with refractory sudden sensorineural hearing loss.

To explore the relationships between glucocorticoid (GC) sensitivity and the prognosis of refractory sudden sensorineural hearing loss (SSNHL), and to analyze the related factors being affected the pr...

Poly-Lactic Acid-Based Biopolymer Formulations Are Safe for Sustained Intratympanic Dexamethasone Delivery.

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Clinical Practice Guideline: Sudden Hearing Loss (Update).

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Clinical Practice Guideline: Sudden Hearing Loss (Update) Executive Summary.

Sudden hearing loss is a frightening symptom that often prompts an urgent or emergent visit to a health care provider. It is frequently, but not universally, accompanied by tinnitus and/or vertigo. Su...

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Medical and Biotech [MESH] Definitions

A water-soluble ester of METHYLPREDNISOLONE used for cardiac, allergic, and hypoxic emergencies.

Sensorineural hearing loss which develops suddenly over a period of hours or a few days. It varies in severity from mild to total deafness. Sudden deafness can be due to head trauma, vascular diseases, infections, or can appear without obvious cause or warning.

A PREDNISOLONE derivative with similar anti-inflammatory action.

An anti-inflammatory 9-fluoro-glucocorticoid.

An anti-inflammatory, anti-allergic glucocorticoid that can be administered orally, by inhalation, locally, and parenterally. It may cause water and salt retention.

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Hearing
Hearing, auditory perception, or audition is the ability to perceive sound by detecting vibrations, changes in the pressure of the surrounding medium through time, through an organ such as the ear. Sound may be heard through solid, liquid, or gaseous mat...


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